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Table 1 Haemodynamic and physiological parameters

From: A cardiopulmonary bypass with deep hypothermic circulatory arrest rat model for the investigation of the systemic inflammation response and induced organ damage

 

T1

T2

T3

T4

T5

Haematocrit (%)

35.8 (±1.9)

17.3 (±1.0)

14.3 (±2.4)

11.9 (±3.4)

9.4 (±2.6)

Haemoglobin (g/dl)

12.3 (±0.4)

6.4 (±0.3)

5.9 (±0.5)

5.7 (±0.6)

4.5 (±1.0)

WBC (x10 3 /mm 3 )

5.0 (±2.1)

1.9 (±0.7)

1.7 (±0.7)

3.1 (±0.7)

2.7 (±0.9)

WBC/Hct (x10 3 /mm 3 )

5.0 (±2.1)

3.7 (±1.3)

3.8 (±1.5)

11.9 (±3.9)

24.2 (±14.4)

WBC/Hct ratio

1.0 (±0.0)

1.2 (±0.5)

1.0 (±0.3)

8.1 (±3.1)

11.9 (±7.2)

Heart rate (bpm)

294.7 (±4.9)

44.7 (±10.2)

82.5 (±27.7)

208.0 (±26.7)

228.3 (±52.2)

MAP (mmHg)

60.5 (±5.7)

53.7 (±7.4)

64.8 (±9.4)

51.8 (±4.9)

59.7 (±3.5)

sO 2 (%)

95.8 (±0.7)

95.3 (±3.8)

96.0 (±0.0)

100.0 (±0.0)

87.5 (±6.5)

Temperature (°C)

36.1 (±0.3)

17.5 (±0.7)

20.0 (±0.0)

35.0 (±0.0)

36.4 (±0.4)

pO 2 (mmHg)

48.2 (±0.9)

47.7 (±3.3)

47.3 (±5.2)

48.8 (±4.4)

44.4 (±4.8)

pCO 2 (mmHg)

2.7 (±0.4)

0.3 (±0.0)

0.5 (±0.2)

1.0 (±0.2)

1.1 (±0.3)

pH

7.27 (±0.03)

7.09 (±0.19)

7.39 (±0.21)

7.33 (±0.10)

7.35 (±0.07)

BE (mmol/L)

-5.6 (±1.12)

-7.7 (±3.4)

-12.7 (±2.4)

-12.5 (±3.2)

-10.0 (±3.1)

HCO 3 (mmol/L)

20.7 (±1.2)

21.8 (±0.9)

12.5 (±1.5)

13.8 (±3.4)

15.2 (±3.0)

  1. At defined time points before CPB (T1), after 25 minutes of cooling (T2), at 20°C during the rewarming (T3), at 35°C during the rewarming (T4) and after 60 minutes of reperfusion (T5) haemodynamic and physiological parameters are measured. WBC = white blood cells; Hct = haematocrit; WBC/Hct ratio = WBC count as a value normalized to the respective Hct and normalized to the start values; bpm = beats per minute; MAP = mean arterial pressure; sO2 = arterial oxygen saturation; pO2 = partial pressure of oxygen; pCO2 = partial pressure of carbon dioxide; BE = base excess; HCO3 = standard bicarbonate. Data represent means ± SEM of six independent experiments.