Effect of CypA on CD147 expression by cultured mouse macrophages. Macrophage cultures were treated with CypA (100–500 ng/mL) for 24 h. Representative western blots (top panel) and densitometric analysis (bottom panel) of CD147 in the cultured macrophages. β-actin was used as an internal control. Band intensities were quantified by scanning densitometry and the data are expressed as relative ratio of CypA treatment to vehicle treatment (vehicle). Values are the means ± S.E.M. (n = 7) *P < 0.05, significantly different from vehicle.