T-cell numbers were reduced in MLN in H . bilis - infected Mdr1a−/−mice treated with anti-IL-7Rα M595. Mesenteric lymph nodes (MLN) were harvested from mice and cells were stained with antibodies to identify T-cell subsets by flow cytometry. Total lymphoid cellularity was determined using Advia Hematology Analyzer. (A) Total cellularity, (B) number of CD4+ cells, (C) number of CD8+ cells, (D) CD4+ to CD8+ T-cell ratio, (E) naïve (CD44-CD62Lhi) to activated/memory (CD44+CD62Llow) CD4+ T-cell ratio, (F) naïve (CD44-) to activated/memory (CD44+) CD8+ T-cell ratio. ANOVA followed by Tukey’s post-test or multivariate t method. *p < 0.05, **p < 0.001, ***p <0.0001.