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Table 2 Cytokine induction ratio is increased in Crry −/− EAMG mice

From: Complement regulatory protein Crry deficiency contributes to the antigen specific recall response in experimental autoimmune myasthenia gravis

Cytokine (fold increase) TNF IL-4 IL-6 IL-17
Crry −/− EAMG / WT EAMG 3.17 3.27 2.71 2.74
  1. Crry deficiency in EAMG was associated with increased serum levels of the pro-inflammatory TNF as well as IL-4, IL-6 and IL-17. Cytokine induction ratio (fold increase) in Crry −/− EAMG group was calculated as follows. An average serum cytokine concentration in Crry −/− EAMG was divided by serum cytokine concentration in WT EAMG mice (Day 63 post primary immunization).