Complement regulatory protein Crry deficiency contributes to the antigen specific recall response in experimental autoimmune myasthenia gravis

Table 2 Cytokine induction ratio is increased in Crry ^−/− EAMG mice

Cytokine (fold increase)	TNF	IL-4	IL-6	IL-17
Crry ^−/− EAMG / WT EAMG	3.17	3.27	2.71	2.74

Crry deficiency in EAMG was associated with increased serum levels of the pro-inflammatory TNF as well as IL-4, IL-6 and IL-17. Cytokine induction ratio (fold increase) in Crry ^−/− EAMG group was calculated as follows. An average serum cytokine concentration in Crry ^−/− EAMG was divided by serum cytokine concentration in WT EAMG mice (Day 63 post primary immunization).

ISSN: 1476-9255