Figure 6

Stimulated PBMCs derived from subjects on OMD and TMD diets were examined for MCP-1 and MIP-1β expression. Production of MCP-1 and MIP-1β could be detected in the culture supernatant from un-stimulated PBMCs. The LPS-induced MCP-1 and MIP-1β release from PBMCs was significantly lower at one month time point in subjects fed OMD versus TMD (p < 0.05). The data are expressed in pg/ml (+/-SEM). The numbers of subjects (n) examined for each stage of the study are as follows: Pre-treatment/Baseline (n = 15), 1 meal/1 month (n = 8), 1 meal/2 month (n = 12), Off-diet (n = 12), 3 meals/1 month (n = 12) and 3 meal/2 month (n = 12).