Table 4 Cytokine concentration (pg/ml) in plasma and BALf post-OVA in WT vs.
From: Triple selectin knockout (ELP-/-) mice fail to develop OVA-induced acute asthma phenotype
Plasma | Mean | |
|---|---|---|
WT | ELP-/- | |
IL-2 | 41.6 ± 7 | 4.95 ± 1.75* |
IFN-γ | 40.89 ± 1.19 | 2.86 ± 0.88* |
TNF-α | 9.1 ± 0.4 | nd |
IL-10 | 78.05 ± 22.65 | 6.55 ± 3.05* |
IL-4 | 81.95 ± 0.85 | nd |
IL-5 | 244.8 ± 22.8 | 87.7 ± 6.6* |
IL-13 | 136.1 ± 0.8 | nd |
Eotaxin | 337.33 ± 40.32 | nd |
MMP-9 | 96696.45 ± 158.11 | 70603 ± 40399.7* |
SDF-1α | 665.6 ± 73.7 | 48.65 ± 7.55* |
KC | 23.8 ± 2 | nd |
TGF-β | 19063.55 ± 4377.45 | nd |
BALf | Mean | |
WT | ELP-/- | |
IL-2 | 36.6 ± 0.7 | 38.4 ± 0.2 |
IFN-γ | 144 ± 27.5 | nd |
TNF-α | 20.4 ± 0.8 | 5.2 ± 0.6* |
IL-10 | 8.7 ± 0.6 | 2.15 ± 0.15* |
IL-4 | 94.75 ± 9.35 | nd |
IL-5 | 94.85 ± 13.35 | 10.1 ± 0.8* |
IL-13 | 131.8 ± 3.9 | 9.1 ± 8.3* |
Eotaxin | 431 ± 84.7 | 12 ± 0.2* |
MMP-9 | 945.3 ± 23.9 | 371.05 ± 67.25* |
SDF-1α | 260.8 ± 17.5 | 35.75 ± 2.95* |
KC | 17.9 ± 0.6 | 6.95 ± 0.45* |
TGF-β | 467 ± 15.7 | nd |