Figure 4
Serca2 mRNA and Ip3r mRNA express in different group. Serca2 mRNA in asthmatic rat ASMC decreased compared with normal ASMC (P < 0.05). But after induced by WIN62577 the expression of Serca2 mRNA increased (P < 0.05). In asthmatic ASMC, we found that Ip3r mRNA had no difference compared with normal ASMC (P > 0.05). In contrast, the expression of Ip3r mRNA decreased after induced by WIN62577 in asthmatic ASMC (P < 0.05). *P < 0.05, control vs normal group; #P < 0.05, control vs asthmatic group; â–²P > 0.05, control vs normal group. N: representive ASMC from control group; A: representive asthmatic ASMC group untreated by WIN62577; NK: representive asthmatic ASMC after WIN62577 treated.