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Figure 4 | Journal of Inflammation

Figure 4

From: Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function

Figure 4

Abolition of PI3Kγ and δ signalling enables budesonide to protect lung Mi-2α expression after cigarette smoke exposure. Mi-2α expression levels in the lung were protected by budesonide treatment in both the PI3KδD910/A910 mice and the PI3Kγ-/- mice but not the WT mice. Data represents the mean ± S.E.M (n = 7-8). *** p > 0.001 compared to air exposed sham. Abbreviations; Smoke: Smoke Exposed; Bud: Budesonide.

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