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Figure 2 | Journal of Inflammation

Figure 2

From: The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFκB signaling pathway and nitric oxide induction in macrophages

Figure 2

Effect of AS101 on degradation and phosphorylation of IKBα in RAW264.7 macrophages. (A,D) Cells were treated with LPS in the absence or in the presence of AS101 for 1 h (A) and 4 h (D). Total cellular proteins were prepared and immunoblotted using anti-pIKBαser32/36, anti-IKBα and anti-actin. Bar graphs represent the quantitative densitometric value of the expressed protein vs actin: pIKBαser32/36 1 h (B) and 4 h (E), IKBα- 1 h (C) and 4 h (F). *p < 0.05 vs LPS. Data shown are representative of three different experiments.

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Journal of Inflammation

ISSN: 1476-9255

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