Figure 2

RNA expression of angiotensin I converting enzyme, ACE (A), angiotensin II type I receptor, AT1R (B) and p22phox (C) in WKY, SHR, WKY treated with captopril (WKYCPT) and SHR treated with captopril (SHRCPT). Values are expressed as means ± SEM (n = 6). The quantitative fold changes in mRNA expression were determined as relative to GAPDH mRNA levels in each corresponding group and calculated using the 2^-ΔΔCT method. ***P < 0.001 vs. WKY; ^##P < 0.01, ^###P < 0.001 vs. SHR.