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Table 1 Statistical analysis of erythema and oedema scores*.

From: Anti-inflammatory activity of nanocrystalline silver-derived solutions in porcine contact dermatitis

Assay

Time (h)

ANOVA

Post Test Results

Erythema

0

p < 0.0001

Negative control < Positive Control (p < 0.001)

   

Negative control < pH 4 (p < 0.001)

   

Negative control < pH 5.6 (p < 0.001)

   

Negative control < pH 7 (p < 0.001)

   

Negative control < pH 9 (p < 0.001)

Erythema

24

p = 0.0018

Negative control < Positive Control (p < 0.01)

   

Negative control < pH 4 (p < 0.05)

   

Negative control < pH 5.6 (p < 0.01)

   

Negative control < pH 7 (p < 0.05)

Erythema

48

p < 0.0001

Negative control < Positive Control (p < 0.001)

   

Negative control < pH 4 (p < 0.001)

   

Negative control < pH 5.6 (p < 0.001)

   

Negative control < pH 7 (p < 0.001)

   

Negative control < pH 9 (p < 0.001)

   

pH 9 < Positive Control (p < 0.01)

   

pH 9 < pH 4 (p < 0.05)

   

pH 9 < pH 5.6 (p < 0.01)

Erythema

72

p < 0.0001

Negative control < Positive Control (p < 0.001)

   

Negative control < pH 4 (p < 0.001)

   

Negative control < pH 5.6 (p < 0.001)

   

Negative control < pH 7 (p < 0.001)

   

pH 9 < Positive Control (p < 0.01)

   

pH 9 < pH 4 (p < 0.05)

   

pH 9 < pH 5.6 (p < 0.05)

Oedema

0

p < 0.0001

Negative control < Positive Control (p < 0.001)

   

Negative control < pH 4 (p < 0.001)

   

Negative control < pH 5.6 (p < 0.001)

   

Negative control < pH 7 (p < 0.001)

   

Negative control < pH 9 (p < 0.001)

Oedema

24

p = 0.0007

Negative control < Positive Control (p < 0.01)

   

Negative control < pH 4 (p < 0.01)

   

Negative control < pH 5.6 (p < 0.001)

   

Negative control < pH 7 (p < 0.01)

   

Negative control < pH 9 (p < 0.01)

Oedema

48

p < 0.0001

Negative control < Positive Control (p < 0.001)

   

Negative control < pH 4 (p < 0.001)

   

Negative control < pH 5.6 (p < 0.001)

   

Negative control < pH 7 (p < 0.001)

   

Negative control < pH 9 (p < 0.001)

   

pH 4 < Positive Control (p < 0.05)

   

pH 7 < Positive Control (p < 0.01)

   

pH 9 < Positive Control (p < 0.001)

   

pH 4 < pH 5.6 (p < 0.05)

   

pH 7 < pH 5.6 (p < 0.01)

   

pH 9 < pH 5.6 (p < 0.001)

Oedema

72

p = 0.0001

Negative control < Positive Control (p < 0.001)

   

Negative control < pH 4 (p < 0.001)

   

Negative control < pH 5.6 (p < 0.01)

   

Negative control < pH 7 (p < 0.05)

   

pH 9 < Positive Control (p < 0.01)

   

pH 9 < pH 4 (p < 0.05)

  1. *Statistical analyses were performed using one-way ANOVAs with Tukey-Kramer Multiple Comparisons Post Tests. All treatment groups were compared in an ANOVA, and if the ANOVA indicated significant differences were present between groups, each treatment group was compared to every other treatment group in post testing. Only statistically significant post test results are shown. Any treatment group comparisons not listed were not significantly different from one another (p > 0.05).
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Journal of Inflammation

ISSN: 1476-9255

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