Table 1 Secretion of cytokines and growth hormones after stimulation of adipose tissue, differentiated adipocytes, or pre-adipocytes with thrombin.

IL-1β

24 h secretion

2.0 ± 1^a

0.2 ± 0.1

1062 ± 721

% induction

616 ± 341

717 ± 453

195 ± 74

IL-6

24 h secretion

4638 ± 1756^a

272 ± 201^a

54682 ± 10734

% induction

3100 ± 1400

2274 ± 1041

22 ± 13

TNF-α

24 h secretion

7.7 ± 4.5^a

0.5 ± 0.5

168 ± 97

% induction

906 ± 522

25 ± 20

44 ± 30

MCP-1

24 h secretion

521 ± 167^a

951 ± 577^a

14421 ± 6996

% induction

520 ± 370

2451 ± 842

144 ± 64

FGF-2

24 h secretion

4.8 ± 2.1^a

1.3 ± 1.2

287 ± 104

% induction

195 ± 106

52 ± 44

202 ± 140

PDGF

24 h secretion

1.4 ± 0.9^a

0.7 ± 0.3^a

170 ± 144

% induction

198 ± 28

635 ± 131

77 ± 52

VEGF

24 h secretion

4662 ± 1884^a

13465 ± 10177^a

3783 ± 609^a

% induction

401 ± 96

634 ± 131

134 ± 87