Cadmium induced expression of Cox-2, IL-6, p-STAT3 and p-Akt. Cell lysate from control and treatment lung were subjected to western blot analysis and ELISA. A, Expression of Cox-2, IL-6, p-STAT3, p-Akt were increased throughout all the experimental period. Though Ibuprofen reduced the expression of Cox-2 and IL-6, but it could not be able to revert the expression of p-STAT3 and p-Akt. B, Bar graphs represent the quantitative densitometric value of the expressed protein. C, OD values showed significant increasement of Cox-2 and IL-6 expression by ELISA. Data is representative of three comparable experiments and indicate p < 0.05 with respect to the control.