Effect of Cadmium on CyclinD1 expression. A, Expression of CyclinD1 was increased throughout all the experimental period. B, Bar graphs represent the quantitative densitometric value of the expressed protein. Data is representative of three comparable experiments indicate p < 0.05 with respect to the control. C, Immunoprecipitation showed the formation CyclinD1-Cdk4 complex, which is an indication of cell cycle progression.