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Table 2 Overview of anti-IgE and ionomycin-induced release of histamine (ng/ml), LTC4/LTD4/LTE4 (ng/ml) and PGD2 (pg/ml) after 30 minutes in the nasal polyp (n = 8) and inferior turbinate group (n = 8).

From: Enhanced release of IgE-dependent early phase mediators from nasal polyp tissue

  Histamine (ng/ml LTC4/LTD4/LTE4 (ng/ml) PGD2 (pg/ml)
Nasal polyps    
RPMI 24.1 (15.1–32.6) 0.0815 (0.048–0.11) 109 (66.5–221)
Versus P < 0.01 P < 0.01 P < 0.01
Anti-igE 10 μg/ml 43.2 (28.1–55.5) 0.469 (0.348–0.816) 1960 (1518–4544)
Versus P < 0.01 P < 0.01 P < 0.01
Anti-IgE 30 μg/ml 63.6 (44.8–75.5) 0.675 (0.561–1.21) 4949 (2991–6152)
Ionomycin 10 μM 130 (77.5–135) 3.40 (1.80–5.37) 2717 (1364–4298)
Versus baseline P < 0.01 P < 0.01 P < 0.01
Inferior turbinates    
RPMI 8.5 (5.6–12.9) 0.036 (0.016–0.0395) 58.6 (40.2–88.2)
Versus P < 0.01 P < 0.01 P < 0.01
Anti-igE 10 μg/ml 16.2 (12.0–20.2) 0.0655 (0.038–0.181) 840 (492–1269)
Versus P < 0.05 P = 0.44 P < 0.05
Anti-IgE 30 μg/ml (n = 6) 28.1 (21.8–31.7) 0.0715 (0.058–0.331) 1669 (1311–1732)
Ionomycin 10 μM 27.6 (22.3–45.5) 0.361(0.24–0.525) 967 (548–1373)
Versus baseline P < 0.01 P < 0.01 P < 0.01
  1. Statistical analysis; Wilcoxon-test
  2. Data are expressed as median +/- IQR.