Figure 2
From: NAC and DTT promote TGF-β1 monomer formation: demonstration of competitive binding
NAC and DTT do not consistently reduce TGF-β mRNA synthesis from human monocytes. Monocytes (10 × 106 per condition) were treated with 2 mM NAC, 20 mM NAC, 1 mM DTT, or 10 mM DTT and incubated for 24 hours. Data points represent fold induction over non-stimulated; mean is represented by horizontal bar. Only DTT 10 mM reduced TGF-β mRNA versus non-stimulated control cells (p < 0.05) other conditions were not significantly different statistically. This data represents three independent studies.