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Figure 2 | Journal of Inflammation

Figure 2

From: Comparative effects of the herbal constituent parthenolide (Feverfew) on lipopolysaccharide-induced inflammatory gene expression in murine spleen and liver

Figure 2

IL-6 mRNA expression levels in spleen and liver following parthenolide and LPS co-treatment. Female B6C3F1 mice were co-treated with parthenolide (5 mg/kg, i.p.) or 50 μl DMSO and LPS (1 mg/kg, i.p.) or 100 μl water. Spleen and liver were collected after 90 minutes and total RNA was extracted and subjected to real-time, one-step RT-PCR using TaqMan primers and probes. IL-6 mRNA levels were normalized using 18S rRNA and related to spleen control values. (a) indicates a significant difference compared to vehicle and parthenolide controls; (b) indicates a significant difference compared to LPS. Data are mean ± SEM (n = 16, controls n = 4), and is a combination of 4 separate experiments.

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Journal of Inflammation

ISSN: 1476-9255

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