Functional characterisation of human pulmonary monocyte-like cells in lipopolysaccharide-mediated acute lung inflammation

Table 3 Cell surface antigen expression by PMLC subpopulations in BAL fluid following LPS inhalation

ANTIGEN	EXPRESSED BY	rPMLC	iPMLC
Ki67	Proliferating cells	19.0 [18.5 – 42.1]	2.1 [0.7 – 8.4]**
CD71 (transferrin receptor)	Mature macrophages	20.3 [15.7 – 31.7]	2.8 [1.5 – 3.6]***
CD206 (mannose receptor)	Alternatively activated macrophages	86.7 [72.8 – 97.9]	61.9 [40.6 – 73.9]*
CD163	Alternatively activated macrophages	92.2 [56.4 – 98.5]	69.6 [29.1 – 91.9]^NS
25 F9	Mature macrophages	89.8 [73.1 – 97.0]	57.3 [14.4 – 97.5]^NS

Data are expressed as median [interquartile range (IQR)] % of cells expressing each marker; n = 12; statistical analysis by Mann Whitney U test; ^NSnon-significant, *P < 0.05, **P < 0.005, ***P < 0.0005.

ISSN: 1476-9255