Figure 4
From: TLR2 stimulation induces cardiac inflammation but not cardiac depression in vivo
PRR and cytokine mRNA expression in hearts of WT mice 4 h after stimulation with different TLR ligands as detected by RPA. B, C, D: LTA stimulation (15 mg/kg, i.p) resulted in a significant increase of mRNA expression of TLR2, TNF-α and IL-1β. A-F: LPS stimulation (20 mg/kg, i.p.) led to a significant increase among all investigated parameters. B, E: CpG-ODN stimulation (1 nmol/g, i.p.) induced a significant increase of TNF-α and TLR2 expression (Values are expressed as arbitrary units, AU; p < 0.05; n = 4; mean ± SEM).