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Figure 5 | Journal of Inflammation

Figure 5

From: A hexadecylamide derivative of hyaluronan (HYMOVIS®) has superior beneficial effects on human osteoarthritic chondrocytes and synoviocytes than unmodified hyaluronan

Figure 5

HA dose response on MMP-13 activity and protein. Dose response of the effect of unmodified HA (black) or the hexadecylamide derivative of HA (white) on APMA-activated MMP13 activity in the culture media after exposure to IL-1β (2 ng/mL) for 24 hours in HSF (A) or HAC (B). P < 0.05 # different from IL-1, no HA control; ‡ different between the amide derivative and unmodified HA at the same concentration. (C) Western blot of MMP-13 protein in pooled media from HAC incubated with and without unmodified or the hexadecylamide derivative of HA at the indicated concentrations. Migration of pre-stained molecular mass markers (kDa) is shown on the left.

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Journal of Inflammation

ISSN: 1476-9255

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