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Figure 4 | Journal of Inflammation

Figure 4

From: A hexadecylamide derivative of hyaluronan (HYMOVIS®) has superior beneficial effects on human osteoarthritic chondrocytes and synoviocytes than unmodified hyaluronan

Figure 4

Effect of pre-incubation on the HA dose response of HSF gene expression. Dose response on expression of the indicated genes of the hexadecylamide derivative of HA added simultaneously with (black markers, dashed line) or 1 hour before (white markers, solid line) the addition of IL-1β (2 ng/mL) in cultures of HSF. P < 0.05 for differences from cultures with IL-1β alone (no added HA; #) or differences +/− pre-incubation (§). Values are mean log fold-change from control (no IL-1 no HA; black dot) from five separate patients.

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