Table 1 Basal clinical data of each study group, and clinical findings at IRIS onset
N | Male/female | Age | HIV ARN copies/mL | CD4 T cells/μl | %CD8 T cells | Onset time (days) | Previous infections | Concomitant infections | |
|---|---|---|---|---|---|---|---|---|---|
No IRIS | 17 | 16/1 | 34.6 (30.5-39.9) | 5.7 (4.9-5.9) | 73.3 (33.1-109.8) | 69 (65.3-75) | PCP, pulmonary TB, hairy leukoplakia, oral candidosis, herpes simplex, MAC, community-acquired pneumonia, persistent diarrhea, chickenpox, herpes zoster, aseptic meningitis | Herpes zoster, molluscum contagiosum, warts, xerosis, community-acquired pneumonia, MAC | |
All IRIS | 17 | 16/1 | 35.5 (31–41) | 5.4 (5–5.8) | 35 (10.5-94.5) | 74 (62–80) | 55 (35.8-70.5) | ||
TB | 6 | 6 | 33.4 (27.9-35.8) | 5.2 (5.1-5.7) | 61.5 (5–132) | 76 (73–79) | 55.5 (53–56) | Chicken pox, molluscum contagiosum, PCP, pulmonary tuberculosis, oral candidosis, MAC | Recurrent chickenpox |
Other IRIS | 11 | 10/1 | 36 (34.4-44.6) | 5.4 (5–5.9) | 35 (13.8-85.5) | 74 (57–84.3) | 52 (31.3-97.5) | ||
HS | 1 | 36 | 4.3 | 185 | 77 | 35 | Condylomata, oral candidosis | Warts, condylomata | |
CMV | 3 | 30.6 (30–42) | 5 (5–5.4) | 35 (13.25-62.75) | 63 (34.5-80.3) | 56 (53–72.5) | Pulmonary and ocular CMV, PCP, oral candidosis, HIV retinopathy, skin KS, | Molluscum contagiosum, warts, skin KS, rash, xerosis | |
HZ | 3 | 46.9 (40.8-49.7) | 5.9 (5.6-5.9) | 38 (5–80) | 74 (48.3-74) | 133 (111.3-178) | Molluscum contagiosum, PCP, MAC, cheilosis | Community-acquired pneumonia, cheilosis | |
KS | 1 | 35 | 6 | 90 | 55 | 41 | Chickenpox | Eczema, xerosis | |
MAC | 3 | 2/1 | 35.2 (34.5-39.1) | 5.4 (4.8-5.8) | 12 (6.8-17.3) | 86 (80.8-91.3) | 28 (21.3-29.5) | PCP, chickenpox, KS, CMV retinitis, molluscum contagiosum | CMV retinitis, perivascular dermatitis |