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Table 1 Basal clinical data of each study group, and clinical findings at IRIS onset

From: Transient expansion of activated CD8+ T cells characterizes tuberculosis-associated immune reconstitution inflammatory syndrome in patients with HIV: a case control study

  N Male/female Age HIV ARN copies/mL CD4 T cells/μl %CD8 T cells Onset time (days) Previous infections Concomitant infections
No IRIS 17 16/1 34.6 (30.5-39.9) 5.7 (4.9-5.9) 73.3 (33.1-109.8) 69 (65.3-75)   PCP, pulmonary TB, hairy leukoplakia, oral candidosis, herpes simplex, MAC, community-acquired pneumonia, persistent diarrhea, chickenpox, herpes zoster, aseptic meningitis Herpes zoster, molluscum contagiosum, warts, xerosis, community-acquired pneumonia, MAC
All IRIS 17 16/1 35.5 (31–41) 5.4 (5–5.8) 35 (10.5-94.5) 74 (62–80) 55 (35.8-70.5)   
TB 6 6 33.4 (27.9-35.8) 5.2 (5.1-5.7) 61.5 (5–132) 76 (73–79) 55.5 (53–56) Chicken pox, molluscum contagiosum, PCP, pulmonary tuberculosis, oral candidosis, MAC Recurrent chickenpox
Other IRIS 11 10/1 36 (34.4-44.6) 5.4 (5–5.9) 35 (13.8-85.5) 74 (57–84.3) 52 (31.3-97.5)   
HS 1   36 4.3 185 77 35 Condylomata, oral candidosis Warts, condylomata
CMV 3   30.6 (30–42) 5 (5–5.4) 35 (13.25-62.75) 63 (34.5-80.3) 56 (53–72.5) Pulmonary and ocular CMV, PCP, oral candidosis, HIV retinopathy, skin KS, Molluscum contagiosum, warts, skin KS, rash, xerosis
HZ 3   46.9 (40.8-49.7) 5.9 (5.6-5.9) 38 (5–80) 74 (48.3-74) 133 (111.3-178) Molluscum contagiosum, PCP, MAC, cheilosis Community-acquired pneumonia, cheilosis
KS 1   35 6 90 55 41 Chickenpox Eczema, xerosis
MAC 3 2/1 35.2 (34.5-39.1) 5.4 (4.8-5.8) 12 (6.8-17.3) 86 (80.8-91.3) 28 (21.3-29.5) PCP, chickenpox, KS, CMV retinitis, molluscum contagiosum CMV retinitis, perivascular dermatitis