Different patterns of CD38 and HLADR expression within CD8+T cell maturation subpopulations. Percentage of CD38+ HLADR- cells among naive (A), CM (B), and EM (C) CD8+ T cells. Percentage of CD38+ HLADR+ cells among naive (D), CM (E), and EM (F) CD8 T cells throughout the study. Percentage of CD38- HLADR+ cells among naive (G), CM (H), and EM (I) CD8+ T cells. * Significant difference between the TB IRIS and No IRIS groups. # Significant difference between the TB IRIS and Other IRIS groups. ‡ Significant difference between Other IRIS and No IRIS groups. Symbols in brackets denote tendencies (p < 0.1). Two-group differences were determined only when the Kruskal-Wallis test showed overall group effects. Values correspond to each group mean ± 1SEM.