Figure 3

Allergen-specific antibody responses of WT and TRPM2^-/-mice are similar. Serum OVA-specific IgE antibodies in WT and TRPM2^-/- mice following saline or OVA treatment and measured by endpoint ELISA. OVA-IgE antibodies were significantly increased in both OVA-treated WT and TRPM2^-/- mice, but no significant difference was seen between WT and TRPM2^-/- mice. Data represent mean values ± SEM from 10 mice per group (* indicates p < 0.05).