Table 1 Dysregulated pathways after ETS exposure and bleomycin administration
Term ID | Directed Enrichment Score | ||
|---|---|---|---|
Air + PBS vs. ETS + PBS | Air + PBS vs. Air + BLM | Air + PBS vs. ETS + BLM | |
ECM Degradation | 0.6191 | 3.3332 | 4.8184 |
Collagen Biosynthesis & Modification | -1.6072 | 3.0188 | 4.7557 |
ECM Synthesis | -1.5301 | 2.3663 | 3.7661 |
PDGF Signaling | -1.8479 | 1.364 | 2.3733 |
SASP | 1.4557 | 0.8054 | 2.3648 |
Myofibroblast Regulation | -1.1383 | 0.3302 | 1.8717 |
Complement Activation | -0.3492 | 0.4872 | 1.621 |
Wnt | 1.0543 | -2.2748 | -3.0824 |