Fig. 6

Removing of p16-positive cells did not recover bleomycin-induced body weight decline and impaired lung function.p16-3MR mice (5 months and 17 months) exposed to ETS for 30 days, administered with BLM and GCV for 14 days. A Illustration of animal treatment in this study. B Body weight was monitored during 14 days post-BLM (C) Lung mechanics (Resistance, Compliance, and Elastance) were measured during the sacrifice at day 14 post-BLM. D Radiant efficiency was measured via IVIS during sacrifice. Data were presented as mean ± SEM (n=2/young group n=3-4/old group)