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Fig. 2 | Journal of Inflammation

Fig. 2

From: Environmental tobacco smoke exposure exaggerates bleomycin-induced collagen overexpression during pulmonary fibrogenesis

Fig. 2

ETS exposure exaggerates collagen overexpression induced by bleomycin. Total RNA isolated from lung homogenates of young C57BL/6J mice (5 months old) was used to identify fibrotic gene transcript levels via NanoString nCounter Fibrosis panel. RNA expression levels were normalized by nSolver software, and the normalized count was used for statistical analysis. Dysregulated gene expression was shown as a heatmap focused on ECM protein and collagen dynamics. Selected gene expression is shown as bar graphs. Data are shown as mean ± SEM (n=6/group *P<0.05, **P<0.01, ***P<0.001 compared with Air+PBS group; # P<0.05, # # P<0.01, # # # P<0.001 compared with Air+BLM group; + P<0.05, ++ P< 0.01, +++ P<0.001 compared with ETS+PBS group)

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Journal of Inflammation

ISSN: 1476-9255

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