Fig. 6From: Anti-hyperalgesic and anti-inflammatory effects of 4R-tobacco cembranoid in a mouse model of inflammatory pain4R effects as a function of time. (a) Diagram of 4R effects in males and females as a function of time. Effects on peripheral hyperalgesia (red line) and paw edema (pink line for males and purple line for females) are shown relative to previously published pharmacokinetics [68] (blue line)Back to article page