Skip to main content
Fig. 5 | Journal of Inflammation

Fig. 5

From: Colchicine prevents oxidative stress-induced endothelial cell senescence via blocking NF-κB and MAPKs: implications in vascular diseases

Fig. 5

Colchicine mitigates the relative mRNA expression of SASP factors. Relative mRNA expression of (A) IL-1β, (B) IL-6, (C) IL-8, (D) MCP-1, (E) ICAM-1, (F) VCAM-1 (G) E-Selectin, (H) MMP-1, (I) MMP-2 (J) MMP-8, (K) MMP-11, (L) TIMP-1 and (M) TIMP-2. (N) Western blot showing protein expression of MMP-2. (O) Relative protein expression of MMP-2. β-actin was used as a loading control. qPCR data are the mean of three independent technical replicates and WB data are the mean of the biological triplicates. The data was analyzed by applying One-way ANOVA followed by Tukey’s test. Error bars represent the SD, *** p < 0.001, ** p < 0.01, and * p < 0.05)

Back to article page

Journal of Inflammation

ISSN: 1476-9255

Contact us