From: Levels of mannose-binding lectin (MBL) associates with sepsis-related in-hospital mortality in women
All patients (n = 148) | Men (n = 57) | Women (n = 91) | |
---|---|---|---|
Age years | 60.7 (IQR 18.3) | 63.4 (IQR 16.5) | 57.2 (IQR 18.0) |
Years between survey and sepsis | 6.5 (IQR 7.7) | 7.4 (IQR 7.8) | 5.9 (IQR 8.1) * |
BMI (n = 116, 52/64) | 26.7 (IQR 6.0) | 26.0 (IQR 6.2) | 26.9 (IQR 7.0) |
Disease scores | |||
APACHE II Score | 18.0 (IQR 9) | 17.0 (IQR 10) | 18.0 (IQR 9) |
SOFA score | 7.0 (IQR 5) | 7.0 (IQR 5) | 7.0 (IQR 6) |
Disease severity, n (%) | |||
Severe sepsis | 99 (66.9%) | 42 (74%) | 57 (63%) |
Septic shock | 49 (33.1%) | 15 (26%) | 34 (37%) |
ICU mortality | 27 (18.2%) | 10 (17.5%) | 17 (18.7%) |
Hospital mortality | 32 (21.6%) | 13 (22.8%) | 19 (20.9%) |
Hospital Length of stay | 17.5 (IQR 24.7) | 15 (IQR 25.5) | 18 (IQR 27) |
Co-morbidities, n (%) | |||
COPD | 4 (2.7%) | 1 (1.8%) | 3 (3.3%) |
Congestive heart failure | 5 (3.4%) | 3 (5.3%) | 2 (2.2%) |
Chronic renal insufficiency | 4 (2.7%) | 2 (3.5%) | 2 (2.2%) |
Chronic liver disease | 0 (0%) | 0 (0%) | 0 (0%) |
Diabetes, n (%) | |||
Insulin treatment | 11 (7.4%) | 4 (7.0%) | 7 (7.7%) |
Other treatments | 8 (5.4%) | 4 (7.0%) | 4 (4.4%) |
Cancer, n (%) | |||
Hematological | 9 (6.1%) | 4 (7.0%) | 5 (5.5%) |
Localized | 20 (13.5%) | 9 (15.8%) | 11 (12.1%) |
Metastatic | 11 (7.4%) | 5 (8.8%) | 6 (6.6%) |
Immunosuppressants, n (%) | |||
Chronic steroids | 8 (5.4%) | 3 (5.3%) | 5 (5.5%) |
Chemotherapy | 13 (8.8%) | 7 (12.3%) | 6 (6.6%) |
Other immunosuppression | 12 (8.1%) | 4 (7.0%) | 8 (8.8%) |
Primary infection site, n (%) | |||
Pneumonia | 24 (16.2%) | 11 (19%) | 13 (14%) |
Abdominopelvic | 50 (33.8%) | 19 (33%) | 31 (34%) |
Urinary tract | 20 (13.5%) | 10 (18%) | 10 (11%) |
Other | 52 (35.1%) | 17 (30%) | 35 (38%) |
Unknown | 5 (3.4%) | 2 (3.5%) | 3 (3.3%) |
Infecting microorganism, n (%) | |||
Gram positive (cocci) | 62 (14.0%) | 23 (40.4%) | 39 (42.9%) |
Gram negative (rods) | 40 (27%) | 21 (36.8%) | 19 (20.9%) * |
Fungi | 11 (7.4%) | 3 (5.3%) | 8 (8.8%) |
Virus | 9 (6.1%) | 3 (5.3%) | 6 (6.6%) |
Negative cultures | 33 (22.3%) | 13 (22.8%) | 20 (22.0%) |