Fig. 4From: The effect of high glucose on the inhibitory action of C21, a selective AT2R agonist, of LPS-stimulated tissue factor expression in human mononuclear cellsAntagonism by PD123,319 (○,10−6M), a selective AT2R blocker [26], of C21-mediated inhibition (♦) of LPS(100 ng/ml)-induced Tissue Factor procoagulant activity in normal (left panel, NG, 5.5 mM) and high (right panel, HG, 50 mM) glucose conditions. Mean ± SD, n = 6 experiments per group. ! p < 0.001 vs. vehicle; *p < 0.001 C21 (♦) vs C21+ PD123,319 (○)Back to article page