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Table 1 M. leprae effect on the MFI of M1 surface markers

From: Mycobacterium leprae alters classical activation of human monocytes in vitro

 

Phenotypic markers

 

CCR7

CD40

CD80

M1 cells

248.0 ± 31.7

51.6 ± 6.3

765.0 ± 64.2

Lep5 (5 h)/M1

167.1** ± 22.6

40.4* ± 6.5

681.9 ± 77.6

Lep20 (5 h)/M1

152.2* ± 7.9

46.3 ± 7.8

591.0* ± 70.1

Unstimulated cells

44.3** ± 1.7

6.5*** ± 0.3

16.6*** ± 2.8

 Lep5

48.4** ± 1.6

7.8*** ± 0.3

20.3*** ± 2.8

 Lep20

49.3** ± 1.4

7.8** ± 0.4

25.3*** ± 3.3

  1. The values represent the mean MFI ± Sem of 4–7 independent experiments (independent donors) for each condition. The statistical significance is shown as compared to the M1 cells. Lep5 (M. leprae MOI 5:1); Lep20 (M. leprae MOI 20:1).*P ≤ 0.05; **P ≤ 0.001 and ***P ≤ 0.0001