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Figure 1 | Journal of Inflammation

Figure 1

From: Differential induction of inflammatory cytokines by dendritic cells treated with novel TLR-agonist and cytokine based cocktails: targeting dendritic cells in autoimmunity

Figure 1

Cocktail screening and donor variation for IL-12p70 and TNFα secretion. A total of 15 different donor-derived imDCs were treated with LPS (0.1 μg/mL) or the 9 cocktails as indicated in table 1. After 24 h of incubation, IL-12p70 and TNFα levels in the conditioned media was determined by ELISA. A) The amount of IL-12p70 protein in each donor is indicated by a dot, and the average of all 15 donors indicated by a horizontal bar. B) Amount of TNFα protein was determined similarly in the 15 donors. Data were analyzed using unpaired, two sided t-test, (***P < 0.005, **P < 0.01, *P < 0.05).

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Journal of Inflammation

ISSN: 1476-9255

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