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Table 1 Cytokine expression and release in LPS-treated mice- Summary

From: Characterization of protein tyrosine phosphatase H1 knockout mice in animal models of local and systemic inflammation

LPS-treated KO vs WT

 

Minutes post-injection

 

30

60

180

Cytokines

Gene

protein

gene

protein

gene

protein

TNFα

=

=

-

-

=

=

MCP-1

=

-

- (ns)

-

=

=

IL6

=

- (ns)

=

- (ns)

=

=

IL12p70

=

-

=

=

=

=

IL 10

nn

-

nn

-

nn

=

  1. Summary of the CBA and RT-PCR results in LPS-treated PTPH1-WT and KO mice at different time points (30, 60 and 180 minutes post- injection). = indicates no variation between WT and KO LPS-treated mice; - indicates a lower expression/release in LPS-treated KO compared to WT matched ones; - (ns) indicates a trend in lower expression/release in LPS-treated KO compared to WT matched ones; nn indicates non-performed.