Figure 1

Carrageenan-induced paw edema in PTPH1-WT and KO mice. Paw edema was detectable at 1h after treatment in both genotypes at the same intensity. This increased thickness of the paws was maintained till sacrifice, at 24h post CARR-injection. No genotype-related differences were detectable between WT and KO CARR-treated groups. 2way Anova followed by Paired T-test *:p<0.05; **:p<0.01; ***:p<0.001. V-WT: vehicle-treated PTPH1-WT mice; C-WT: CARR-treated PTPH1-WT mice; V-KO: vehicle-treated PTPH1-KO mice; C-KO: CARR-treated PTPH1-KO mice.