Figure 6

and immunohistochemical localization of TNF-α in pancreas, lung and gut. 18 hours following zymosan injection, a positive TNF-α staining was found in pancreas (A), lung (B) and gut (C). There was no detectable immunostaining for TNF-α in pancreas (D), lung (E) and gut (F) of zymosan-treated mice when mice were treated with GW0742. Figures are representative of at least 3 experiments performed on different experimental days.