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Figure 2 | Journal of Inflammation

Figure 2

From: CCR5 signalling, but not DARC or D6 regulatory, chemokine receptors are targeted by herpesvirus U83A chemokine which delays receptor internalisation via diversion to a caveolin-linked pathway

Figure 2

U83A does not displace human chemokines binding to scavenger receptors D6 and DARC. Cells transiently expressing D6 (A and B) or DARC (C and D) were used to investigate the binding of U83A to these receptors, monitored by displacement of [125I] CCL5 (A and C) or CCL3 (B and D). Positive controls were performed using cold forms of the radiolabelled chemokine, showing significant displacement of the radiolabelled form, (A) P < 0.05, (B) P < 0.01, (C and D) P < 0.001, unpaired T test.

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Journal of Inflammation

ISSN: 1476-9255

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