Affiliated with the British Inflammation Research Association (BIRAs).
Citation: Journal of Inflammation 2015 12(Suppl 1):O10
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Citation: Journal of Inflammation 2015 12(Suppl 1):O10
Citation: Journal of Inflammation 2015 12(Suppl 1):P8
Citation: Journal of Inflammation 2015 12(Suppl 1):O8
Citation: Journal of Inflammation 2015 12(Suppl 1):O7
Citation: Journal of Inflammation 2015 12(Suppl 1):P6
Citation: Journal of Inflammation 2015 12(Suppl 1):O5
Citation: Journal of Inflammation 2015 12(Suppl 1):P4
Citation: Journal of Inflammation 2015 12(Suppl 1):O3
Citation: Journal of Inflammation 2015 12(Suppl 1):P2
Citation: Journal of Inflammation 2015 12(Suppl 1):P1
Citation: Journal of Inflammation 2015 12(Suppl 1):O1
To investigate whether monosodium urate (MSU) crystals induce interleukin (IL)-1β in human fibroblast-like synoviocytes (FLS), and whether the NLRP3 inflammasome is involved in the inflammatory mechanism.
Citation: Journal of Inflammation 2015 12:30
Recently adipokines have been implicated in the regulation of immune and inflammatory responses in autoimmune disease. To investigate the role of adipokines in adult and pediatric patients with newly diagnosed...
Citation: Journal of Inflammation 2015 12:29
Sarcoidosis is a granulomatous disease affecting in particular the lungs. The peroxisome proliferator-activated receptors (PPARs) play important regulatory roles in inflammation. The aim of this study was to g...
Citation: Journal of Inflammation 2015 12:28
Up-regulation of regulated upon activation, normal T-cell expressed and secreted (RANTES/CCL5) and adhesion molecules is observed in the serum of animals following experimental subarachnoid hemorrhage (SAH). T...
Citation: Journal of Inflammation 2015 12:27
Chronic Kidney Disease (CKD) and inflammation are risk factors for atherosclerotic vascular disease (ASVD). In inflammatory conditions, Nuclear Factor-κB (NF-κB) is frequently activated and it has been detecte...
Citation: Journal of Inflammation 2015 12:26
We aimed to investigate peripheral blood eosinophil chemotaxis, generation of spontaneous reactive oxygen species (ROS), and apoptosis in patients with allergic asthma after bronchial allergen challenge.
Citation: Journal of Inflammation 2015 12:25
Cartilage damage is a crucial step in rheumatoid arthritis (RA) disease progress while its molecular mechanisms are not fully understood. Here we investigated the expression of hedgehog (Hh) signal pathway in ...
Citation: Journal of Inflammation 2015 12:24
To explore the immunological mechanisms underlying the effect of chronic intermittent hypobaric hypoxia (CIHH) pretreatment on collagen-induced arthritis (CIA) in rat.
Citation: Journal of Inflammation 2015 12:23
Apolipoprotein A-IV (apoA-IV) is a protein mainly synthesized by enterocytes in the intestine. Its gene expression is suppressed during fasting and stimulated during active fat absorption. Chronic feeding of a...
Citation: Journal of Inflammation 2015 12:22
Sarcoidosis is a systemic disease of unknown etiology characterized histologically by the observation of non-caseating granulomas and several immunological abnormalities. Sarcoidosis is a multi-organ disorder ...
Citation: Journal of Inflammation 2015 12:21
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and progressive decline in pulmonary function. Neutrophil-to-lymphocyte ratio (NLR), YKL-40 and calprotectin are biomarkers...
Citation: Journal of Inflammation 2015 12:20
Inflammatory bowel disease is an immunologically mediated disease. Notably, it is less common in countries where there is a greater risk of exposure to helminths. In our study, we examined the modulatory effec...
Citation: Journal of Inflammation 2015 12:19
Interleukin 6 (IL-6) is a major pro-inflammatory cytokine and dysregulation of IL-6 is relevant to many inflammatory diseases. Endotoxin induced tolerance of IL-6 is an important mechanism to avoid the excessi...
Citation: Journal of Inflammation 2015 12:18
In inflammatory joint disease, such as osteoarthritis or arthritis, there is an increased level of pro-inflammatory cytokines, such as interleukin-1β. These cytokines stimulate the expression and release of ma...
Citation: Journal of Inflammation 2015 12:17
Human parainfluenza virus type 3 (HPIV3), while infecting lower airway epithelial cells induces pneumonia and bronchiolitis in infants and children, and may lead to asthma exacerbations in children and adults....
Citation: Journal of Inflammation 2015 12:16
Atherosclerosis, the underlying cause of heart attack and strokes, is a progresive dyslipidemic and inflammatory disease where monocyte-derived macrophage cells play a pivotal role. Although most of the mechan...
Citation: Journal of Inflammation 2015 12:15
Ionizing radiation (IR) activates both pro-and anti-proliferative signal pathways producing an imbalance in cell fate decision. IR is able to regulate several genes and factors involved in cell-cycle progressi...
Citation: Journal of Inflammation 2015 12:14
Nuclear receptor 4A2 (NR4A2) is an orphan nuclear receptor and constitutively active transcription factor expressed at elevated levels in inflamed joint tissues from patients with arthritis. Inflammatory media...
Citation: Journal of Inflammation 2015 12:13
The oxidative stress response is a cellular defense mechanism that protects cells from oxidative damage and cancer development. The exact molecular mechanism by which reactive oxygen species (ROS) contribute t...
Citation: Journal of Inflammation 2015 12:12
Delayed M1 toward M2 macrophage phenotype transition is considered one of the major causes for the impaired healing after myocardial infarction (MI). While searching for molecules that modulate M1 and M2 macro...
Citation: Journal of Inflammation 2015 12:11
Adipose cells responsible for fat storage are the targets of reactive oxygen species (ROS) like H2O2 and pro-inflammatory agents including TNFα and LPS. Such mediators contribute to oxidative stress and alter inf...
Citation: Journal of Inflammation 2015 12:10
Genetic studies have pointed out that CD226 variants, encoding DNAM-1, could be associated with susceptibility to rheumatoid arthritis. Therefore, we aimed to determine the influence of DNAM-1 on the development ...
Citation: Journal of Inflammation 2015 12:9
Obesity is regarded as a risk factor for cardiovascular disease. Bone morphogenetic protein 4 (BMP4) is a proinflammatory and profibrotic factor, and the reduced expression of this molecule in obese mice seems...
Citation: Journal of Inflammation 2015 12:8
Mutations in the Mevalonate Kinase gene (MVK) are causes of a rare autoinflammatory disease: Mevalonate Kinase Deficiency and its more acute manifestation, Mevalonic Aciduria. The latter is characterized, among o...
Citation: Journal of Inflammation 2015 12:7
Sulforaphane has well established anti-cancer properties and more recently anti-inflammatory properties have also been determined. Sulforaphane has been shown to inhibit PRR-mediated pro-inflammatory signallin...
Citation: Journal of Inflammation 2015 12:6
In sub-Saharan Africa poly-parasite infections are frequently observed in children, and with poly-parasitism modulating immune mechanisms, mediated by cytokines and chemokines, are required to prevent overwhel...
Citation: Journal of Inflammation 2015 12:5
Plants from the genus Ocimum are used as folk medicine for treating various diseases including inflammatory and immune-related diseases. Numerous reports have suggested plant extracts and their constituents as po...
Citation: Journal of Inflammation 2015 12:4
To explore the upstream signal transduction mechanisms responsible for the imbalanced expression of glucocorticoid receptor (GR) isoforms in chronic rhinosinusitis (CRS) mucosa.
Citation: Journal of Inflammation 2015 12:3
Adenosine is a potent endogenous anti-inflammatory and immunoregulatory molecule. Despite its promise, adenosine’s extremely short half-life in blood limits its clinical application. Here, we examined adenosin...
Citation: Journal of Inflammation 2015 12:2
Milk-derived bioactive peptides retain many biological properties and have therapeutic effects in cardiovascular disorders such as atherosclerosis. Under inflammatory conditions the expression of endothelial c...
Citation: Journal of Inflammation 2015 12:1
It has recently been found that both nuclear epithelial-expressed histone deacetylases Hdac1 and Hdac2 are important to insure intestinal homeostasis and control the mucosal inflammatory response in vivo. In addi...
Citation: Journal of Inflammation 2014 11:43
Red palm oil (RPO) and rooibos have been shown to exhibit cardioprotective properties. RPO is rich in essential fatty acids and fat soluble antioxidants while rooibos contains polyphenolic compounds with a uni...
Citation: Journal of Inflammation 2014 11:41
Vocal fold fibroblast’s (VFF) strategic location in the lamina propria and their ability to respond to external stimuli by producing inflammatory molecules suggest their possible direct involvement in innate i...
Citation: Journal of Inflammation 2014 11:42
In human gingival fibroblasts (HGFs), TLR4 recognises Pathogen-associated molecular patterns (PAMPs), such as LPS, and subsequently activates downstream signals that lead to the production of pro-inflammatory ...
Citation: Journal of Inflammation 2014 11:38
Sepsis causes neutrophil sequestration in the lung which leads to acute lung injury (ALI). Radix Ginseng (RG), a traditional herb used as herbal remedy in eastern Asia for thousands of years, which has been tr...
Citation: Journal of Inflammation 2014 11:40
Obesity is the world’s most important public health problem. Adipose tissue contributes significantly to increase pro-inflammatory mediators whose cascade begins with the union of TLR4 to its microbial ligands...
Citation: Journal of Inflammation 2014 11:39
Adenosine is produced at high levels at inflamed sites as a by-product of cellular activation and breakdown. Adenosine mediates its anti-inflammatory activity primarily through the adenosine A2a receptor (A2aR), ...
Citation: Journal of Inflammation 2014 11:37
Hyperglycemia exacerbates brain damage caused by cerebral ischemia. Neuroinflammation may play a role in mediating such enhanced damage. The objectives of this study were to examine the mRNA and protein levels...
Citation: Journal of Inflammation 2014 11:35
The response of the joint to anterior cruciate ligament (ACL) injury has not been fully characterized. In particular, the characterization of both catabolic factors, including interleukin-6 (IL-6), interleukin...
Citation: Journal of Inflammation 2014 11:34
Affiliated with the British Inflammation Research Association (BIRAs).
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78 days to first decision for reviewed manuscripts only
51 days to first decision for all manuscripts
117 days from submission to acceptance
14 days from acceptance to publication
Citation Impact
2.800 - 2-year Impact Factor
3.137 - 5-year Impact Factor
0.920 - Source Normalized Impact per Paper (SNIP)
1.095 - SCImago Journal Rank (SJR)
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