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  1. Physical exercise induces neuroprotection through anti-inflammatory effects and total sleep deprivation is reported an inflammatory process. We examined whether 7 weeks of exercise training attenuates markers ...

    Authors: M. Chennaoui, D. Gomez-Merino, C. Drogou, H. Geoffroy, G. Dispersyn, C. Langrume, S. Ciret, T. Gallopin and F. Sauvet

    Citation: Journal of Inflammation 2015 12:56

    Content type: Research

    Published on:

  2. Unresolved and prolonged inflammation is a pathological basis of many disorders such as cancer and multiple organ failure in shock. Interleukin-1 receptor (IL-1R) superfamily consists of IL-1R1 and pathogen pa...

    Authors: Prachi Vilekar, Geeta Rao, Shanjana Awasthi and Vibhudutta Awasthi

    Citation: Journal of Inflammation 2015 12:55

    Content type: Research

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  3. The activity of one of the major catechins in Green Tea, the polyphenol (−)-epigallocatechin-3-gallate (EGCG), has been shown to have a variety of health benefits. Recent studies suggest that EGCG can modulate...

    Authors: So-Youn Min, Mei Yan, Sang Bum Kim, Sneha Ravikumar, Seong-Ryuel Kwon, Kamala Vanarsa, Ho-Youn Kim, Laurie S. Davis and Chandra Mohan

    Citation: Journal of Inflammation 2015 12:53

    Content type: Research

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  4. Focal cerebral ischemia induces an inflammatory response that when exacerbated contributes to deleterious outcomes. The molecular basis regarding the regulation of the innate immune response after focal cerebr...

    Authors: Frank J. Brand III, Juan Carlos de Rivero Vaccari, Nancy H. Mejias, Ofelia F. Alonso and Juan Pablo de Rivero Vaccari

    Citation: Journal of Inflammation 2015 12:52

    Content type: Research

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  5. Gastric epithelial cells (GECs) undergo apoptosis during H. pylori infection and phagocytes within the mucosa engulf these cells. The recognition and clearance of apoptotic cells is a multifactorial process, enha...

    Authors: Sarah Fox, Kieran A. Ryan, Alice H. Berger, Katie Petro, Soumita Das, Sheila E. Crowe and Peter B. Ernst

    Citation: Journal of Inflammation 2015 12:51

    Content type: Research

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  6. Emerging reports propose possible biomarkers that are related to inflammation, nutrition and lipid parameters for detection of the progression of atherosclerotic plaques, peripheral artery disease (PAD) and pa...

    Authors: Jiexia Chen, Lei Han, Xiaoyan Xu, Haiqin Tang, Hongyan Wang and Bin Wei

    Citation: Journal of Inflammation 2015 12:50

    Content type: Short Report

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  7. Inflammation, angiogenesis and oxidative stress have been implicated in the pathogenesis of various vascular diseases. Recent evidence suggests that dimethylfumarate (DMF), an antiposriatic and anti-multiple s...

    Authors: Simon Gerhardt, Veronika König, Monika Doll, Tsige Hailemariam-Jahn, Igor Hrgovic, Nadja Zöller, Roland Kaufmann, Stefan Kippenberger and Markus Meissner

    Citation: Journal of Inflammation 2015 12:49

    Content type: Short Report

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  8. Rheumatoid arthritis is a chronic inflammatory debilitating disease triggered by a complex interaction involving genetic and environmental factors. Active smoking and occupational exposures such as silica incr...

    Authors: Mickael Essouma and Jean Jacques N. Noubiap

    Citation: Journal of Inflammation 2015 12:48

    Content type: Review

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  9. The aim of the present study is to investigate the effects of two structurally divergent coumarins, calipteryxin (1) and (3’S,4’S)-3’,4’-disenecioyloxy-3’,4’-dihydroseselin (2) from Seseli recinosum, in lipopolys...

    Authors: Salman Khan, Omer Shehzad, Mao-Sheng Cheng, Rui-Juan Li and Yeong Shik Kim

    Citation: Journal of Inflammation 2015 12:47

    Content type: Research

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  10. This study was designed to evaluate the protective effects of thalidomide on paraquat (PQ)-induced lung injuries in a rat model and to explore the underlying mechanisms.

    Authors: Dan Li, Xiao-Wei Zhang, Xing-Quan Jiang, Yong-Jie Yin, Zhe Fan, Cheng-Bo Sun, Xing-Hai Chen, Yan-Hui Li and Ke-Xiang Liu

    Citation: Journal of Inflammation 2015 12:46

    Content type: Research

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  11. Several organs in the body comprise cells coupled into networks. These cells have in common that they are excitable but do not express action potentials. Furthermore, they are equipped with Ca2+ signaling systems...

    Authors: Elisabeth Hansson and Eva Skiöldebrand

    Citation: Journal of Inflammation 2015 12:44

    Content type: Review

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  12. Status epilepticus (SE) can cause neuronal cell death and impaired behavioral function. Acute exposure to potent acetylcholinesterase inhibitors such as soman (GD) can cause prolonged SE activity, micro-hemorr...

    Authors: Erik A. Johnson, Michelle A. Guignet, Thuy L. Dao, Tracey A. Hamilton and Robert K. Kan

    Citation: Journal of Inflammation 2015 12:43

    Content type: Research

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  13. The tristetraprolin (TTP) family of mRNA-binding proteins contains three major members, Ttp, Zfp36l1, and Zfp36l2. Ttp down-regulates the stability of AU-rich element–containing mRNAs and functions as an anti-...

    Authors: Kuan-Ting Wang, Hsin-Hui Wang, Yan-Yun Wu, Yu-Lun Su, Pei-Yu Chiang, Nien-Yi Lin, Shun-Chang Wang, Geen-Dong Chang and Ching-Jin Chang

    Citation: Journal of Inflammation 2015 12:42

    Content type: Research

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  14. Nur77, an orphan member of the nuclear receptor superfamily, has been implicated in the regulation of inflammation. However, the in vivo function of Nur77 remains largely unexplored. In the current study, we inv...

    Authors: Xiu-Ming Li, Xing-Xing Lu, Qian Xu, Jing-Ru Wang, Shen Zhang, Peng-Da Guo, Jian-Ming Li and Hua Wu

    Citation: Journal of Inflammation 2015 12:40

    Content type: Short Report

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  15. Immunomodulatory effects in humans of Δ9−Tetrahydrocannabinol (THC), the psychoactive component of marijuana are controversial. Tissue factor (TF), the activator of the extrinsic coagulation cascade, is increased...

    Authors: Julie C. Williams, Thomas W. Klein, Bruce A. Goldberger, John W. Sleasman, Nigel Mackman and Maureen M. Goodenow

    Citation: Journal of Inflammation 2015 12:39

    Content type: Short Report

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  16. Systemic Lupus Erythematosus (SLE) is an auto-immune disease whose complex pathogenesis remains unraveled. Here we aim to explore the inflammatory ability of SLE patients’ sera upon peripheral blood (PB) monoc...

    Authors: Tiago Carvalheiro, Diane Gomes, Ligia A. Pinto, Luis Inês, Ana Lopes, Ana Henriques, Susana Pedreiro, António Martinho, Hélder Trindade, Howard A. Young, José António Pereira da Silva and Artur Paiva

    Citation: Journal of Inflammation 2015 12:38

    Content type: Research

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  17. There is mounting evidence to support the role of inflammation in benign prostate hyperplasia (BPH), and a recent study reported expression of inflammasome derived cytokine IL-18 in prostate biopsy of BPH pati...

    Authors: Mahendra Kashyap, Subrata Pore, Zhou Wang, Jeffrey Gingrich, Naoki Yoshimura and Pradeep Tyagi

    Citation: Journal of Inflammation 2015 12:37

    Content type: Research

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  18. The nuclear receptors PPAR-γ and LXRs regulate macrophage lipid metabolism and macrophage mediated inflammation. We examined the influence of these molecules on macrophage alternative activation, with particul...

    Authors: Gaetano Zizzo and Philip L Cohen

    Citation: Journal of Inflammation 2015 12:36

    Content type: Research

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  19. Acute ulcerative colitis is an inflammation-driven condition of the bowel. It hampers the general homeostasis of gut, resulting in decreased mucus production and epithelial cell renewal. Adiponectin (APN), an ...

    Authors: Kamaljeet Kaur, Arpit Saxena, Bianca Larsen, Samantha Truman, Nathan Biyani, Emma Fletcher, Manjeshwar Shrinath Baliga, Venkatesh Ponemone, Shweta Hegde, Anindya Chanda and Raja Fayad

    Citation: Journal of Inflammation 2015 12:35

    Content type: Research

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  20. This study was designed to investigate the effect of glucose 6-phosphate dehydrogenase (G6PD) deficiency on pro-inflammatory cytokine secretion using a palmitate-induced inflammation HepG2 in vitro model. The ...

    Authors: Hung-Chi Yang, Mei-Ling Cheng, Yi-Syuan Hua, Yi-Hsuan Wu, Hsin-Ru Lin, Hui-Ya Liu, Hung-Yao Ho and Daniel Tsun-Yee Chiu

    Citation: Journal of Inflammation 2015 12:34

    Content type: Research

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  21. Studies suggest that inflammation is a key factor in the pathogenesis of diabetes mellitus. Pro-inflammatory cytokines, such as IL-6 and TNF-alpha, are produced by adipose tissue in large quantities, in obese ...

    Authors: Francisca Adilfa de Oliveira Garcia, Jéssica Farias Rebouças, Teresa Queiroz Balbino, Teresinha Gonçalves da Silva, Carlson Hélder Reis de Carvalho-Júnior, Gilberto Santos Cerqueira, Gerly Anne de Castro Brito and Glauce Socorro de Barros Viana

    Citation: Journal of Inflammation 2015 12:33

    Content type: Research

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  22. MMP-9 is crucial for a normal immune response, but excessive release of this enzyme leads to severe tissue damage. Listeria monocytogenes (LM) is an opportunistic food-borne pathogen causing listerosis, meningiti...

    Authors: Puthiyaveetil Kochumon Shihab, Areej Al-Roub, Moneera Al-Ghanim, Anfal Al-Mass, Kazem Behbehani and Rasheed Ahmad

    Citation: Journal of Inflammation 2015 12:32

    Content type: Research

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  23. Monocyte chemoattractant protein-1 (MCP-1) is a major chemokine that recruits monocyte/macrophage to the site of tissue injury and plays a critical role in microvascular complications of diabetes. However, the...

    Authors: Huibin Huang, Guangjun Jing, Joshua J Wang, Nader Sheibani and Sarah X Zhang

    Citation: Journal of Inflammation 2015 12:31

    Content type: Research

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  24. Citation: Journal of Inflammation 2015 12(Suppl 1):P4

    Content type: Poster presentation

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  25. To investigate whether monosodium urate (MSU) crystals induce interleukin (IL)-1β in human fibroblast-like synoviocytes (FLS), and whether the NLRP3 inflammasome is involved in the inflammatory mechanism.

    Authors: Shu-cong Zheng, Xiao-xia Zhu, Yu Xue, Li-hong Zhang, He-jian Zou, Jian-hua Qiu and Qiong Liu

    Citation: Journal of Inflammation 2015 12:30

    Content type: Research

    Published on:

  26. Recently adipokines have been implicated in the regulation of immune and inflammatory responses in autoimmune disease. To investigate the role of adipokines in adult and pediatric patients with newly diagnosed...

    Authors: Jeannette M Olazagasti, Molly Hein, Cynthia S Crowson, Consuelo Lopez de Padilla, Erik Peterson, Emily C Baechler and Ann M Reed

    Citation: Journal of Inflammation 2015 12:29

    Content type: Research

    Published on:

  27. Sarcoidosis is a granulomatous disease affecting in particular the lungs. The peroxisome proliferator-activated receptors (PPARs) play important regulatory roles in inflammation. The aim of this study was to g...

    Authors: Muntasir Abo Al Hayja, Anders Eklund, Johan Grunewald and Jan Wahlström

    Citation: Journal of Inflammation 2015 12:28

    Content type: Research

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  28. Up-regulation of regulated upon activation, normal T-cell expressed and secreted (RANTES/CCL5) and adhesion molecules is observed in the serum of animals following experimental subarachnoid hemorrhage (SAH). T...

    Authors: Chih-Zen Chang, Shu-Chuan Wu, Chih-Lung Lin and Aij-Lie Kwan

    Citation: Journal of Inflammation 2015 12:27

    Content type: Research

    Published on:

  29. Chronic Kidney Disease (CKD) and inflammation are risk factors for atherosclerotic vascular disease (ASVD). In inflammatory conditions, Nuclear Factor-κB (NF-κB) is frequently activated and it has been detecte...

    Authors: Miguel Hueso, Joan Torras, Marta Carrera, August Vidal, Estanis Navarro and Josep Grinyó

    Citation: Journal of Inflammation 2015 12:26

    Content type: Short Report

    Published on:

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