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Journal of Inflammation


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  1. Content type: Research

    Adipocyte fatty acid-binding protein, also known as aP2 or fatty acid-binding protein 4 (FABP4), plays an important role in inflammatory and metabolic responses in adipocytes and macrophages. Recent work has d...

    Authors: Qian Wang, Guanglin Shi, Ying Teng, Xia Li, Jin Xie, Qin Shen, Caixin Zhang, Songshi Ni and Zhiyuan Tang

    Citation: Journal of Inflammation 2017 14:8

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  2. Content type: Research

    The dysfunction of articular chondrocytes is a crucial step in rheumatoid arthritis (RA) pathogenesis while its molecular mechanisms are not fully known. This study was aimed to investigate the expression of a...

    Authors: Li Cai, Chao Lei, Rong Li, Wei-na Chen, Cheng-mu Hu, Xiao-yu Chen and Chun-mei Li

    Citation: Journal of Inflammation 2017 14:6

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  3. Content type: Research

    An altered amniotic cytokine profile has been reported in inflammatory pregnancy complications with a leading role for IL-6, a marker of the foetal systemic inflammatory response. Up to this date there is no e...

    Authors: Martina Maritati, Manola Comar, Nunzia Zanotta, Silva Seraceni, Alessandro Trentini, Fabrizio Corazza, Fortunato Vesce and Carlo Contini

    Citation: Journal of Inflammation 2017 14:5

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  4. Content type: Short report

    Peritoneal macrophages are widely used in immunological studies. The cells can be collected under non-elicited (resident) or elicited (e.g., with Brewer thioglycollate broth injection) conditions, and their ph...

    Authors: Sofia Pavlou, Luxi Wang, Heping Xu and Mei Chen

    Citation: Journal of Inflammation 2017 14:4

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  5. Content type: Research

    Statins (HMG CoA reductase inhibitors), in addition to reducing circulating cholesterol and incidence of coronary heart disease, also have pleiotropic, anti-inflammatory effects. Patients with chronic liver di...

    Authors: Peter Fraunberger, Elisabeth Gröne, Hermann-Josef Gröne, Heinz Drexel and Autar K. Walli

    Citation: Journal of Inflammation 2017 14:3

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  6. Content type: Research

    Airway viral infections cause the exacerbations of asthma and chronic obstructive pulmonary disease. PD-L1, also known as B7-H1, is an immune-checkpoint molecule that plays a role in an escape mechanism of vir...

    Authors: Saaka Hamano, Koichiro Matsumoto, Ken Tonai, Satoru Fukuyama, Keiko Kan-o, Nanae Seki, Hiromasa Inoue and Yoichi Nakanishi

    Citation: Journal of Inflammation 2017 14:2

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  7. Content type: Research

    It is well considered that reactive oxygen species (ROS) plays a prominent causative role in the development of allergic rhinitis (AR), and eosinophils cells as important allergic inflammatory cells contribute...

    Authors: Shaoqing Yu, Chuanliang Zhao, Na Che, Lin Jing and Rongming Ge

    Citation: Journal of Inflammation 2017 14:1

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  8. Content type: Research

    The C825T polymorphism (rs5443) of the Guanine Nucleotide-Binding protein subunit β3 (GNB3) gene has been associated with obesity, essential hypertension, atherosclerosis, coronary diseases, and cerebrovascular e...

    Authors: Kokoè Mélinda Gbadoe, Nazha Berdouzi, Alex-Ander Aldasoro Aguiñano, Ndeye Coumba Ndiaye and Sophie Visvikis-Siest

    Citation: Journal of Inflammation 2016 13:39

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  9. Content type: Research

    The innate immune Toll-like receptors (TLRs) 2/4 are important players in chronic low-grade inflammation called metabolic inflammation in obesity and type-2 diabetes (T2D). While TLR2/4 expression changes asso...

    Authors: Rasheed Ahmad, Shihab Kochumon, Reeby Thomas, Valerie Atizado and Sardar Sindhu

    Citation: Journal of Inflammation 2016 13:38

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  10. Content type: Research

    Macrophages serve as intracellular reservoirs of S. aureus. Recent in vitro studies have confirmed high level resistance by S. aureus to macrophage mediated killing and the intracellular persistence of Staphyloco...

    Authors: Somrita Dey and Biswadev Bishayi

    Citation: Journal of Inflammation 2016 13:36

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  11. Content type: Review

    Prostate is an immune-competent organ normally populated by inflammatory cells. Prostatic inflammation origin can be multi-factorial and there are some emerging evidences on its possible role as a factor invol...

    Authors: Alessandro Sciarra, Alessandro Gentilucci, Stefano Salciccia, Federico Pierella, Flavio Del Bianco, Vincenzo Gentile, Ida Silvestri and Susanna Cattarino

    Citation: Journal of Inflammation 2016 13:35

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  12. Content type: Research

    Neuroinflammation (NI) is a key feature in the pathogenesis and progression of infectious and non-infectious neuropathologies, and its amelioration usually improves the patient outcome. Peripheral inflammation...

    Authors: G. Meneses, M. Bautista, A. Florentino, G. Díaz, G. Acero, H. Besedovsky, D. Meneses, A. Fleury, A. Del Rey, G. Gevorkian, G. Fragoso and E. Sciutto

    Citation: Journal of Inflammation 2016 13:33

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  13. Content type: Research

    Osteoarthritis (OA) is described by an imbalance between anabolic and catabolic processes in the affected joint. This dysregulation of metabolism affects not only chondrocytes within cartilage tissue but also ...

    Authors: Christoph Bauer, Eugenia Niculescu-Morzsa, Vivek Jeyakumar, Daniela Kern, Stephan S. Späth and Stefan Nehrer

    Citation: Journal of Inflammation 2016 13:31

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  14. Content type: Research

    Adipokines have a wide range of effects and are linked to sepsis and septic shock. The aim of the present study was to describe the changes in adipokine levels in septic patients in relation to patients’ prese...

    Authors: Andreas Hillenbrand, Pengfei Xu, Shaoxia Zhou, Annette Blatz, Manfred Weiss, Sebastian Hafner, Doris Henne-Bruns and Uwe Knippschild

    Citation: Journal of Inflammation 2016 13:30

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  15. Content type: Research

    Interleukin (IL)-1β is involved in the pathology of intervertebral disc degeneration. Under normal conditions, IL-1β is present in cells in an inactive form (pro-IL-1β). However, under pathological conditions,...

    Authors: Frank J. Brand III, Mahtab Forouzandeh, Harmanpreet Kaur, Francesco Travascio and Juan Pablo de Rivero Vaccari

    Citation: Journal of Inflammation 2016 13:29

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  16. Content type: Research

    Liver regeneration following 70 % partial hepatectomy (PH) requires the coordinated expression of soluble mediators produced by macrophages. Monocyte chemoattractant protein-1 (MCP-1) is a potent stimulus of m...

    Authors: Stephanie L. Wyler, Shawna L. D’Ingillo, Cheri L. Lamb and Kristen A. Mitchell

    Citation: Journal of Inflammation 2016 13:28

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  17. Content type: Research

    Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that are implicated in the regulation of lipid and glucose homeostasis. PPAR agonists have been shown to control i...

    Authors: Julia Naidenow, Igor Hrgovic, Monika Doll, Tsige Hailemariam-Jahn, Victoria Lang, Johannes Kleemann, Stefan Kippenberger, Roland Kaufmann, Nadja Zöller and Markus Meissner

    Citation: Journal of Inflammation 2016 13:27

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  18. Content type: Research

    The pathogenesis of non-allergic rhinitis (NAR) is still largely unknown. Furthermore, it is unclear whether there is a correlation between the effect of nasal glucocorticoids on nasal inflammation and on nasa...

    Authors: Donatella Poletti, Valeria Iannini, Paolo Casolari, Marco Contoli, Alberto Papi, Paul Kirkham, Trevor T. Hansel, Kian Fan Chung, Peter J. Barnes, Antonio Pastore, Stefano Pelucchi, Ian M. Adcock and Gaetano Caramori

    Citation: Journal of Inflammation 2016 13:26

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  19. Content type: Research

    Obesity is associated with vascular inflammation, fibrosis and reduced high-density lipoproteins (HDL)-cholesterol. We aimed to investigate whether adenoviral gene transfer with human apolipoprotein (apo) A-I (Ad...

    Authors: Frank Spillmann, Bart De Geest, Ilayaraja Muthuramu, Ruhul Amin, Kapka Miteva, Burkert Pieske, Carsten Tschöpe and Sophie Van Linthout

    Citation: Journal of Inflammation 2016 13:25

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  20. Content type: Research

    Endotoxemia is commonly reported in patients receiving haemodialysis and implicated in the pathogenesis of systemic inflammation. The Limulus Amoebocyte Lysate (LAL) assay is the most commonly used blood endot...

    Authors: Jonathan Wong, Nathan Davies, Hasan Jeraj, Enric Vilar, Adie Viljoen and Ken Farrington

    Citation: Journal of Inflammation 2016 13:24

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  21. Content type: Short Report

    Behcet’s disease (BD) is characterized by systemic recurrent inflammation with increased production of tumor necrosis factor (TNF)–α and interleukin (IL)-6 by peripheral blood mononuclear cells (PBMCs). To gai...

    Authors: Min-Yeong Woo, Su Jin Yun, Okki Cho, Kyongmin Kim, Eun-So Lee and Sun Park

    Citation: Journal of Inflammation 2016 13:22

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Affiliated with the British Inflammation Research Association (BIRAs).

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