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  1. Idiopathic Pulmonary Fibrosis and Rheumatoid Arthritis associated usual interstitial pneumonia seem to have the same poor outcome as there is not an effective treatment. The aim of the study is to explore the ...

    Authors: Katerina M Antoniou, George A Margaritopoulos, Athanasia Proklou, Konstantinos Karagiannis, Ismini Lasithiotaki, Giannoula Soufla, Maria Christina Kastrinaki, Demetrios A Spandidos, Helen A Papadaki and Nikos M Siafakas
    Citation: Journal of Inflammation 2012 9:27
  2. Persistent vascular inflammation has been implicated as an important cause for a higher prevalence of cardiovascular disease (CVD) in HIV-infected adults. In several populations at high risk for CVD, vascular 18F...

    Authors: Kevin E Yarasheski, Erin Laciny, E Turner Overton, Dominic N Reeds, Michael Harrod, Steven Baldwin and Victor G Dávila-Román
    Citation: Journal of Inflammation 2012 9:26
  3. Barth Syndrome (BTHS) is a serious X-linked genetic disorder associated with mutations in the tafazzin gene (TAZ, also called G4.5). The multi-system disorder is primarily characterized by the following pathol...

    Authors: Lori D Wilson, Sadeeka Al-Majid, Cyril S Rakovski and Christina D Schwindt MD
    Citation: Journal of Inflammation 2012 9:25
  4. Non-invasive imaging of inflammation to measure the progression of autoimmune diseases, such as rheumatoid arthritis (RA), and to monitor responses to therapy is critically needed. V-Sense, a perfluorocarbon (...

    Authors: Anthony Balducci, Brooke M Helfer, Eric T Ahrens, Charles F O’Hanlon III and Amy K Wesa
    Citation: Journal of Inflammation 2012 9:24
  5. Glycogen synthase kinase 3β (GSK3β) plays a fundamental role during the inflammatory response induced by bacteria. Depending on the pathogen and its virulence factors, the type of cell and probably the context...

    Authors: Ricarda Cortés-Vieyra, Alejandro Bravo-Patiño, Juan J Valdez-Alarcón, Marcos Cajero Juárez, B Brett Finlay and Víctor M Baizabal-Aguirre
    Citation: Journal of Inflammation 2012 9:23
  6. Areca nut, the seed of fruit of an oriental palm, known as Areca catechu, is commonly chewed in many countries. Diabetes, hypertension, cardiovascular diseases, oropharyngeal and oesophageal cancers have been ass...

    Authors: Kashif Shafique, Saira Saeed Mirza, Priya Vart, Abdul Rauf Memon, Moin Islam Arain, Muhammad Farooq Tareen and Zia Ul Haq
    Citation: Journal of Inflammation 2012 9:22
  7. We test the hypothesis that intra-coronary tacrolimus administration can limit infarct size and preserve left ventricular ejection fraction (LVEF) after acute myocardial infarction (AMI) through ligating left ...

    Authors: Sarah Chua, Steve Leu, Jiunn-Jye Sheu, Yu-Chun Lin, Li-Teh Chang, Ying-Hsien Kao, Chia-Hung Yen, Tzu-Hsien Tsai, Yung-Lung Chen, Hsueh-Wen Chang, Cheuk-Kwan Sun and Hon-Kan Yip
    Citation: Journal of Inflammation 2012 9:21
  8. Myasthenia gravis (MG) and animal model of experimental autoimmune myasthenia gravis (EAMG) is the most common autoimmune disorder of neuromuscular transmission. The disease is caused by the breakdown of the a...

    Authors: Jindrich Soltys and Xiaobo Wu
    Citation: Journal of Inflammation 2012 9:20
  9. Esenbeckia leiocarpa, a wide spread native Brazilian tree, was reported recently to possess anti-inflammatory effects in vivo, but the mechanisms involved are still not fully understood and its role in neutrophil...

    Authors: Rafael de Liz, Heros Horst, Moacir Geraldo Pizzolatti, Tânia Silvia Fröde and Denis Girard
    Citation: Journal of Inflammation 2012 9:19
  10. Activation of the endothelium, complement activation and generation of cytokines are known events during ischemia-reperfusion (I/R) that mediate tissue injury. Our aim was to elucidate their respective partici...

    Authors: Pranitha Kamat, Bettina Juon, Brigitte Jossen, Thusitha Gajanayake, Robert Rieben and Esther Vögelin
    Citation: Journal of Inflammation 2012 9:18
  11. The goal of the present study was to explore the effect of medications that are commonly prescribed for CKD patients on uremic state.

    Authors: Yuri Tanaka, Nobuhiko Joki, Hiroki Hase, Masaki Iwasaki, Masato Ikeda, Ryoichi Ando, Toshio Shinoda, Daijo Inaguma, Toshifumi Sakaguchi, Yasuhiro Komatsu, Fumihiko Koiwa, Toshihiko Yamaka and Takashi Shigematsu
    Citation: Journal of Inflammation 2012 9:17
  12. The aim of this study was to investigate the hepatoprotective effect of Matrine salvianolic acid B salt on carbon tetrachloride (CCl4)-induced hepatic fibrosis in rats. Salvianolic acid B and Matrine has long bee...

    Authors: Hong-Ying Gao, Guo-Yu Li, Meng-Meng Lou, Xiao-Yu Li, Xiu-Yan Wei and Jin-Hui Wang
    Citation: Journal of Inflammation 2012 9:16
  13. Inflammation in adipose tissue (AT) during obesity causes impaired AT function. Although multiple extracellular matrix (ECM) proteins are expressed in AT their potential role in adipose tissue inflammation is ...

    Authors: Venkata J Adapala, Meliza Ward and Kolapo M Ajuwon
    Citation: Journal of Inflammation 2012 9:15
  14. Murine gammaherpesvirus 68 (HV-68) is an efficient pathogen, capable of infecting and establishing lifelong latency in rodents. While many studies have demonstrated the ability of this viral infection to modul...

    Authors: Daniel A Nelson, Vinita S Chauhan, Melanie D Tolbert and Kenneth L Bost
    Citation: Journal of Inflammation 2012 9:14
  15. Recent findings suggest a role of oxidative stress in the pathogenesis of Behcet's disease (BD), but the utility of oxidative stress-associated assays in offering diagnostic information or in the monitoring of...

    Authors: Yasemin D Akcay, Ferhan G Sagin, Kenan Aksu, Gokhan Keser, Emma Taylor, Iona Knight, Paul G Winyard and Eser Y Sozmen
    Citation: Journal of Inflammation 2012 9:13
  16. Toll-like receptor 4 (TLR4) is activated by bacterial endotoxin, a pathogen-associated molecular pattern (PAMP). It has been suggested that TLR4 can also be activated by damage-associated molecular pattern (DA...

    Authors: Michael Luong, Yanyu Zhang, Tim Chamberlain, Tianhui Zhou, Jill F Wright, Ken Dower and J Perry Hall
    Citation: Journal of Inflammation 2012 9:11
  17. Histone deacetylase (HDAC) is an enzyme that regulates chromatin structure and inflammatory gene expression. In patients with chronic obstructive pulmonary disease (COPD), while accumulating evidence indicates...

    Authors: Yanwei Chen, Ping Huang, Wen Ai, Xiaoli Li, Wei Guo, Jingnong Zhang and Jiong Yang
    Citation: Journal of Inflammation 2012 9:10
  18. Allergic asthma is a chronic inflammatory lung disease that is characterized by airway hyperresponsiveness (AHR) to allergens, airway oedema, increased mucus secretion, excess production of T helper-2 (Th2) cy...

    Authors: Seung-Hyung Kim, Bok-Kyu Kim and Young-Cheol Lee
    Citation: Journal of Inflammation 2012 9:9
  19. Oxidative stress and matrix metalloproteinases -9 and -2 are involved in periodontal breakdown, whereas gingival crevicular fluid has been reported to reflect apical status. The aim of this study was to charac...

    Authors: Andrea Dezerega, Sonia Madrid, Verónica Mundi, María A Valenzuela, Mauricio Garrido, Rodolfo Paredes, Jocelyn García-Sesnich, Ana V Ortega, Jorge Gamonal and Marcela Hernández
    Citation: Journal of Inflammation 2012 9:8
  20. The cellular and molecular mechanisms of inflammatory bowel disease are not fully understood; however, data indicate that uncontrolled chronic inflammation induced by bacterial gene products, including lipotei...

    Authors: Mojgan Zadeh, Mohammad W Khan, Yong Jun Goh, Kurt Selle, Jennifer L Owen, Todd Klaenhammer and Mansour Mohamadzadeh
    Citation: Journal of Inflammation 2012 9:7
  21. Asthma is characterised by increased numbers of Th2-like cells in the airways and IgE secretion. Generation of Th2 cells requires interleukin (IL)-4 and IL-13 acting through their specific receptors and activa...

    Authors: Katsuyuki Tomita, Gaetano Caramori, Kazuhiro Ito, Hiroyuki Sano, Sam Lim, Timothy Oates, Borja Cosio, K Fan Chung, Yuji Tohda, Peter J Barnes and Ian M Adcock
    Citation: Journal of Inflammation 2012 9:5
  22. Inhibitors of Apoptosis (IAP) family play a critical role in apoptosis and inflammatory response. Neuronal Apoptosis Inhibitory Protein (NAIP), as a member of both IAPs and NLR families (NOD-Like Receptor), is...

    Authors: Safoura Mazrouei, Amin Ziaei, Amir Pouya Tanhaee, Kianoosh Keyhanian, Mahdad Esmaeili, Azar Baradaran and Mansoor Salehi
    Citation: Journal of Inflammation 2012 9:4
  23. Oxidative stress is thought to play an important role in the pathogenesis of inflammation. Recent studies have found that hydrogen gas has the effect of eliminating free radicals. Whether hydrogen saline (more...

    Authors: Zheng Xu, Jiangrui Zhou, Jianmei Cai, Zhen Zhu, Xuejun Sun and Chunlei Jiang
    Citation: Journal of Inflammation 2012 9:2
  24. COPD is a disease of innate immunity and bacterial infections are a dominant cause of exacerbations in the later stages resulting in poor health and high mortality. The pathogen-associated molecular pattern (P...

    Authors: Anta Ngkelo, Koremu Meja, Mike Yeadon, Ian Adcock and Paul A Kirkham
    Citation: Journal of Inflammation 2012 9:1
  25. Some of the most serious consequences of normal ageing relate to its effects on skeletal muscle, particularly significant wasting and associated weakness, termed "sarcopenia". The underlying mechanisms of sarc...

    Authors: Chris van der Poel, Luc E Gosselin, Jonathan D Schertzer, James G Ryall, Kristy Swiderski, Meron Wondemaghen and Gordon S Lynch
    Citation: Journal of Inflammation 2011 8:41
  26. Atypical prostatic hyperplasia (APH) is a pseudoneoplastic lesion that can mimic prostate adenocarcinoma because of its cytologic and architectural features. Suspension of date palm pollen (DPP) is an herbal m...

    Authors: Ahmed A Elberry, Shagufta T Mufti, Jaudah A Al-Maghrabi, Essam A Abdel-Sattar, Osama M Ashour, Salah A Ghareib and Hisham A Mosli
    Citation: Journal of Inflammation 2011 8:40
  27. The concept that a strong inflammatory response involving the full complement of cytokines and other mediators is critical for unimpaired healing has been challenged by wound healing studies using transgenic a...

    Authors: Marie AT Matias, Jodi M Saunus, Saso Ivanovski, Laurence J Walsh and Camile S Farah
    Citation: Journal of Inflammation 2011 8:39
  28. This study investigated whether the vitreous fluid levels of soluble vascular endothelial growth factor receptor-2 (sVEGFR-2), pigment epithelium-derived factor (PEDF), and soluble intercellular adhesion molec...

    Authors: Hidetaka Noma, Hideharu Funatsu, Tatsuya Mimura and Shuichiro Eguchi
    Citation: Journal of Inflammation 2011 8:38
  29. Zinc supplementation can modulate immunity through inhibition of NF-κB, a transcription factor that controls many immune response genes. Thus, we sought to examine the mechanism by which zinc supplementation t...

    Authors: Carrie I Morgan, John R Ledford, Ping Zhou and Kristen Page
    Citation: Journal of Inflammation 2011 8:36
  30. Adamantiades-Behçet's disease (ABD) is a chronic multisystemic inflammation with unknown pathophysiology. This disorder is associated with a dysregulation of the cytokine network that hyperactivates neutrophil...

    Authors: Djamel Messaoudene, Houda Belguendouz, Mohamed Laid Ahmedi, Tarek Benabdekader, Fifi Otmani, Malika Terahi, Pierre Youinou and Chafia Touil-boukoffa
    Citation: Journal of Inflammation 2011 8:35
  31. Atherosclerosis is an inflammatory disease that is marked by increased presence of Tumor Necrosis Factor-alpha (TNFα), increased expression of Vascular Cell Adhesion Molecule-1 (VCAM-1), increased presence of ...

    Authors: Daniel Z Mackesy and Marc L Goalstone
    Citation: Journal of Inflammation 2011 8:34
  32. Obesity is characterized by inflammation, caused by increase in proinflammatory cytokines, a key factor for the development of insulin resistance. SR141716A, a cannabinoid receptor 1 (CB1) antagonist, shows si...

    Authors: Ravi Murumalla, Karima Bencharif, Lydie Gence, Amritendu Bhattacharya, Frank Tallet, Marie-Paule Gonthier, Stefania Petrosino, Vincenzo di Marzo, Maya Cesari, Laurence Hoareau and Régis Roche
    Citation: Journal of Inflammation 2011 8:33
  33. Thoracic surgery mandates usually a one-lung ventilation (OLV) strategy with the collapse of the operated lung and ventilation of the non-operated lung. These procedures trigger a substantial inflammatory resp...

    Authors: Andreas Breunig, Franco Gambazzi, Beatrice Beck-Schimmer, Michael Tamm, Didier Lardinois, Daniel Oertli and Urs Zingg
    Citation: Journal of Inflammation 2011 8:32
  34. The collagen antibody-induced arthritis (CAIA) model, which employs a cocktail of monoclonal antibodies (mAbs) to type II collagen (CII), has been widely used for studying the pathogenesis of autoimmune arthri...

    Authors: Thongchai Koobkokkruad, Tatsuya Kadotani, Pilaiwanwadee Hutamekalin, Nobuaki Mizutani and Shin Yoshino
    Citation: Journal of Inflammation 2011 8:31
  35. Rheumatoid arthritis (RA) is a chronic autoimmune disease, which causes synovial damage. Persistence of lymphocyte infiltrates in the rheumatoid synovium has been attributed to abnormal apoptosis. While not co...

    Authors: Devapregasan Moodley, Girish M Mody and Anil A Chuturgoon
    Citation: Journal of Inflammation 2011 8:30
  36. The natural function of the C-C chemokine receptor type 5 (CCR5) is poorly understood. A 32 base pair deletion in the CCR5 gene (CCR5-delta32) located on chromosome 3 results in a non-functional protein. It is...

    Authors: Gero Hütter, Martin Neumann, Daniel Nowak, Stefan Klein, Harald Klüter and Wolf-K Hofmann
    Citation: Journal of Inflammation 2011 8:29
  37. Stroke models are essential tools in experimental stroke. Although several models of stroke have been developed in a variety of animals, with the development of transgenic mice there is the need to develop a r...

    Authors: Silvia Mora-Lee, Ma Salomé Sirerol-Piquer, María Gutiérrez-Pérez, Tania López, Mayte Casado-Nieto, Carlos Jauquicoam, Gloria Abizanda, Miriam Romaguera-Ros, Ulises Gomez-Pinedo, Felipe Prósper and José-Manuel García-Verdugo
    Citation: Journal of Inflammation 2011 8:28
  38. Numerous reports have identified therapeutic roles for plants and their extracts and constituents. The aim of this study was to assess the efficacies of three plant extracts for their potential antioxidant and...

    Authors: Tamsyn SA Thring, Pauline Hili and Declan P Naughton
    Citation: Journal of Inflammation 2011 8:27
  39. Excessive secretion of IL-8 characterizes cystic fibrosis (CF). This has been attributed to excessive activation of epithelial cell I-κB Kinase and/or NFκB. Maximum IL-8 production requires 3 cooperative mecha...

    Authors: Aicha Saadane, Jean Eastman, Melvin Berger and Tracey L Bonfield
    Citation: Journal of Inflammation 2011 8:26
  40. The kynurenine pathway (KP) is the main route of tryptophan degradation in the human body and generates several neuroactive and immunomodulatory metabolites. Altered levels of KP-metabolites have been observed...

    Authors: Linnéa Asp, Anne-Sofie Johansson, Amandeep Mann, Björn Owe-Larsson, Ewa M Urbanska, Tomasz Kocki, Magdalena Kegel, Göran Engberg, Gabriella BS Lundkvist and Håkan Karlsson
    Citation: Journal of Inflammation 2011 8:25
  41. Dercum's disease (DD) is characterised by obesity and chronic pain (> 3 months) in the adipose tissue. The pathogenesis of DD is unknown, but inflammatory components have been proposed. In previous reports and...

    Authors: Emma Hansson, Henry Svensson, Unne Stenram and HÃ¥kan Brorson
    Citation: Journal of Inflammation 2011 8:24
  42. Arterial peripheral disease is a condition caused by the blocked blood flow resulting from arterial cholesterol deposits within the arms, legs and aorta. Studies have shown that macrophages in atherosclerotic ...

    Authors: Camila R Corrêa, Luciane A Dias-Melicio, Sueli A Calvi, Sidney Lastória and Angela MVC Soares
    Citation: Journal of Inflammation 2011 8:23
  43. Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is expressed by mainly stromal cells, such as epithelial and endothelial cells, and its expression is upregulated following pro-inf...

    Authors: Ashley M Miller
    Citation: Journal of Inflammation 2011 8:22
  44. Rheumatoid arthritis (RA) is an inflammatory, polyarticular joint disease. A number of cellular responses are involved in the pathogenesis of rheumatoid arthritis, including activation of inflammatory cells an...

    Authors: Hiroshi Okamoto and Akiko Kobayashi
    Citation: Journal of Inflammation 2011 8:21
  45. We investigated the association between polymorphisms of the angiotensin converting enzyme-1 (ACE-1) and angiotensin II type one receptor (AT1RA1166C) genes and the causation of renal disease in 76 advanced ch...

    Authors: Manal F Elshamaa, Samar M Sabry, Hafez M Bazaraa, Hala M Koura, Eman A Elghoroury, Nagwa A Kantoush, Eman H Thabet and Dalia A Abd-El Haleem
    Citation: Journal of Inflammation 2011 8:20

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