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Fig. 3 | Journal of Inflammation

Fig. 3

From: First trimester human umbilical cord perivascular cells (HUCPVC) modulate the kynurenine pathway and glutamate neurotransmission in an LPS-induced mouse model of neuroinflammation

Fig. 3

HUCPVC modulate LPS-induced microglial activation. Representative images showing positive immunostaining of microglial activation marker, ionized calcium-binding adapter molecule 1 IBA1 (green), in the hippocampus (A,B,C) and cortex (D,E,F) in the brain cryosections of control (A,D), LPS (B,E) and LPS + HUCPVC (C,F) groups. Nuclei counterstained with DAPI (blue). Scale bar = 50 μm. The mean percent area of IBA1 positive signal in the hippocampus (G) and cortex (H) was assessed by Image J analysis, n = 3 per group. *p < 0.05, **p < 0.005, ***p < 0.0005, one-way ANOVA with Tukey’s multiple comparison tests

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Journal of Inflammation

ISSN: 1476-9255

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