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Fig. 2 | Journal of Inflammation

Fig. 2

From: Dioscin alleviates the progression of osteoarthritis: an in vitro and in vivo study

Fig. 2

Dio suppresses IL-1β-induced inflammatory cytokines expression in chondrocytes. Chondrocytes were exposed to IL-1β (10 ng/mL) with or without Dio (200, 400, and 800 ng/mL) for 24 h. A Griess reaction was used to determine the NO concentration. B PGE2 level was detected by ELISA. C Gene expressions of COX-2 and iNOS were detected by qRT-PCR. D Representative western blots and (E) quantitative analysis of COX-2 and iNOS in each group. #P < 0.05 vs. control group; *P < 0.05 vs. IL-1β group; **P < 0.01 vs. IL-1β group; n = 3

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