Fig. 4

Formation of lung oedema expressed as (A) wet-dry lung weight ratio (W/D) and (B) protein content in BAL fluid (mg/mL) in healthy ventilated animals (Control; n = 8), in animals with ARDS (ARDS; n = 8) and in ARDS animals treated with aminophylline (ARDS/AMINO; n = 8). Data are presented as mean ± SD. Statistical comparisons: for ARDS vs. Control ****p < 0.0001; for ARDS/AMINO vs. ARDS ⁺p < 0.05, ⁺⁺⁺p < 0.001