Fig. 3

Levels of (A) a marker of oxidative modifications of proteins (expressed in nanomolar concentration of 3-nitrotyrosine, 3NT), (B) a marker of lipid oxidation (thiobarbituric acid-reactive substances, TBARS, expressed in micromolar concentration of malondialdehyde), and (C) total antioxidant capacity (TAC, expressed in micromolar concentration of copper reducing equivalents (CRE)) in the lung tissue of healthy ventilated animals (Control; n = 8), in animals with ARDS (ARDS; n = 8) and ARDS animals treated with aminophylline (ARDS/AMINO group; n = 8) after 4 h therapy. Data are presented as mean ± SD. Statistical comparisons: for ARDS vs. Control **p < 0.01, ***p < 0.001; for ARDS/AMINO vs. ARDS ⁺p < 0.05, ⁺⁺⁺p < 0.001; ⁺⁺⁺⁺p < 0.0001