Fig. 1From: Anti-inflammatory activity of non-selective PDE inhibitor aminophylline on the lung tissue and respiratory parameters in animal model of ARDSChanges in the respiratory parameters. (A) Ratio of the partial pressure of oxygen to the fraction of inspired oxygen (P/F ratio, kPa), (B) Oxygenation index (OI), (C) Ventilation efficiency index (VEI), and (D) Dynamic lung compliance (Cdyn, mL/kPa) before (basal value, BV) and after induction of ARDS and within 4 h after the therapy administration in the Control group (n = 8), ARDS group (n = 8), and ARDS group treated with aminophylline (ARDS/AMINO; n = 8). Data are presented as mean ± SD. Statistical comparisons: for ARDS vs. Control ****p < 0.0001; for ARDS/AMINO vs. ARDS +p < 0.05, ++p < 0.01, +++p < 0.001; ++++p < 0.0001Back to article page