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Fig. 1 | Journal of Inflammation

Fig. 1

From: Anti-inflammatory activity of non-selective PDE inhibitor aminophylline on the lung tissue and respiratory parameters in animal model of ARDS

Fig. 1

Changes in the respiratory parameters. (A) Ratio of the partial pressure of oxygen to the fraction of inspired oxygen (P/F ratio, kPa), (B) Oxygenation index (OI), (C) Ventilation efficiency index (VEI), and (D) Dynamic lung compliance (Cdyn, mL/kPa) before (basal value, BV) and after induction of ARDS and within 4 h after the therapy administration in the Control group (n = 8), ARDS group (n = 8), and ARDS group treated with aminophylline (ARDS/AMINO; n = 8). Data are presented as mean ± SD. Statistical comparisons: for ARDS vs. Control ****p < 0.0001; for ARDS/AMINO vs. ARDS +p < 0.05, ++p < 0.01, +++p < 0.001; ++++p < 0.0001

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