Fig. 7

Modulation of IL-6 production and cell viability by selective MAO inhibition. IL-6 production and cell viability of RASFs treated with different concentrations of the MAO-A inhibitor clorgyline (CLG, n = 6) (a, b) or the MAO-B inhibitor lazabemide hydrochloride (LB, n = 5) (c, d). RASFs were pre-treated with TNF for 72 hours (red) or left untreated (black). MAO-A and MAO-B inhibitors were applied thereafter for 24 hours. * p < 0.05, ** p < 0.01, *** p < 0.001, comparing with the control group without MAOs inhibitors by one-way ANOVA with Tukey’s multiple comparison test