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Fig. 5 | Journal of Inflammation

Fig. 5

From: Components of the sympathetic nervous system as targets to modulate inflammation – rheumatoid arthritis synovial fibroblasts as neuron-like cells?

Fig. 5

Dopamine and norepinephrine modulate interleukin (IL)-6 production and cell viability of RASFs. IL-6 production (a, upper panel) and cell viability (a, lower panel) after stimulation with dopamine (DA, 10 nM – 100 μM) for 24 hours (n = 6). IL-6 production (b, upper panel) and cell viability (b, lower panel) after stimulation with norepinephrine (NE, 10 nM – 100 μM) for 24 hours. (n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001, for comparisons with the control group (without DA or NE) by one-way ANOVA with Tukey’s post-hoc test

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