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Fig. 3 | Journal of Inflammation

Fig. 3

From: Progranulin (PGRN) as a regulator of inflammation and a critical factor in the immunopathogenesis of cardiovascular diseases

Fig. 3

Comparison between normal conditions and hyperhomocysteinemia in the proximal tube and bowman capsule with focus on the role of PGRN. The absence of PGRN In hyperhomocysteinemia activates the Wnt/β-catenin signaling pathway, which play a significant role in this pathological condition. However, presence of PGRN under normal conditions suppresses the Wnt/β-catenin expression

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Journal of Inflammation

ISSN: 1476-9255

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