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Table 1 Clinical features and baseline characteristics between two groups

From: Extracellular vesicles isolated from hyperuricemia patients might aggravate airway inflammation of COPD via senescence-associated pathway

 

Total

COPD(N = 37)

COPD + HUA(N = 31)

P-value

Age

68.41 ± 8.77

68.65 ± 1.04

68.13 ± 2.00

0.8099

Gender (Male/Female)

55/13

27/10

28/3

0.070

BMI

22.81 ± 4.38

21.55 ± 0.71

24.33 ± 0.73

0.0080

Pulmonary function

 PreFEV1

69.86 ± 28.97

85.61 ± 4.64

51.06 ± 2.82

 < 0.0001

 PreFVC

78.51 ± 21.78

83.15 ± 4.34

73.04 ± 3.06

0.0703

 PreFEV1/FVC

75.42 ± 20.28

83.86 ± 2.94

65.33 ± 3.32

0.0001

 Post-FEV1

69.99 ± 19.21

82.68 ± 14.56

60.97 ± 15.357

0.4399

 PostFVC

78.45 ± 25.87

83.83 ± 17.64

74.10 ± 10.71

0.6077

 Post-FEV1/FVC

75.56 ± 23.44

84.43 ± 17.16

66.74 ± 14.40

0.7026

Hemogram indices

 SUA

376.23 ± 133.04

284.46 ± 11.57

485.75 ± 18.67

 < 0.0001

 ALT

20.86 ± 17.79

18.58 ± 1.14

23.58 ± 4.53

0.2519

 AST

21.53 ± 16.96

20.02 ± 1.14

23.32 ± 4.32

0.4294

 EGFR

92.92 ± 26.68

99.00 ± 3.93

85.86 ± 5.15

0.0436

 Scr

79.08 ± 36.11

67.62 ± 2.62

92.75 ± 8.53

0.0035

 CRP

22.06 ± 42.72

9.39 ± 2.15

37.19 ± 10.53

0.0066

 ALB

42.28 ± 7.77

42.27 ± 1.40

42.30 ± 1.23

0.9898

 CRP/ALB

0.62 ± 1.62

0.21 ± 0.04

1.11 ± 0.42

0.0218

  1. Abbreviation: COPD chronic obstructive pulmonary disease, HUA hyperuricemia, SUA serum uric acid, BMI body mass index, FEV1 forced expiratory volume in one second, FVC forced vital capacity, CRP C-reactive protein, ALT alanine transaminase, AST aspartate transaminase, ALB albumin, EGFR estimated Glomerular Filtration Rate, SCR serum creatinine